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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LANCL1
All Species:
31.82
Human Site:
Y250
Identified Species:
53.85
UniProt:
O43813
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43813
NP_001130046.1
399
45283
Y250
L
V
K
P
S
V
D
Y
V
C
Q
L
K
F
P
Chimpanzee
Pan troglodytes
XP_516065
399
45271
Y250
L
V
K
P
S
V
D
Y
V
C
Q
L
K
F
P
Rhesus Macaque
Macaca mulatta
XP_001110118
399
45249
Y250
L
V
K
P
S
V
D
Y
V
C
Q
L
K
F
P
Dog
Lupus familis
XP_536055
399
45422
Y250
L
V
K
P
S
V
D
Y
V
C
Q
L
K
F
P
Cat
Felis silvestris
Mouse
Mus musculus
O89112
399
45323
F250
L
V
K
P
S
V
D
F
V
C
R
L
K
F
P
Rat
Rattus norvegicus
Q9QX69
399
45221
F250
L
V
K
P
S
V
D
F
V
C
Q
L
K
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508377
456
51270
Y307
V
V
K
P
S
V
D
Y
V
C
R
L
K
F
P
Chicken
Gallus gallus
NP_001026416
343
38587
S203
R
R
N
F
A
T
K
S
P
L
M
Y
E
W
Y
Frog
Xenopus laevis
NP_001082380
402
45423
Y253
L
V
R
P
S
M
E
Y
V
R
C
L
K
F
P
Zebra Danio
Brachydanio rerio
Q90ZL2
405
45733
Y256
L
V
K
P
S
V
N
Y
V
C
Q
L
K
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y7
419
47592
K258
A
A
E
L
R
D
I
K
R
S
I
D
F
F
L
Honey Bee
Apis mellifera
XP_624030
404
46400
F256
D
I
R
P
A
L
D
F
L
Q
N
L
R
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797679
400
44476
Y261
L
I
K
P
T
V
D
Y
I
L
E
L
R
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149305
401
44438
P255
Y
M
I
K
N
K
F
P
S
G
N
Y
P
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.7
91.2
N.A.
91.4
91.4
N.A.
54.1
68.6
68.4
64.6
N.A.
36.2
40.8
N.A.
49
Protein Similarity:
100
99.7
100
95.7
N.A.
96.4
95.4
N.A.
66.6
78.1
81.8
78.5
N.A.
54.1
62.3
N.A.
66
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
86.6
0
66.6
93.3
N.A.
6.6
33.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
86.6
100
N.A.
13.3
80
N.A.
93.3
Percent
Protein Identity:
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
55.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
58
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
65
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
8
22
0
0
0
0
8
86
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
8
0
0
0
8
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
65
8
0
8
8
8
0
0
0
0
65
0
0
% K
% Leu:
65
0
0
8
0
8
0
0
8
15
0
79
0
0
8
% L
% Met:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
8
0
0
0
15
0
0
0
0
% N
% Pro:
0
0
0
79
0
0
0
8
8
0
0
0
8
0
79
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
43
0
0
0
0
% Q
% Arg:
8
8
15
0
8
0
0
0
8
8
15
0
15
0
0
% R
% Ser:
0
0
0
0
65
0
0
8
8
8
0
0
0
8
8
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
65
0
0
0
65
0
0
65
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
8
0
0
0
0
0
0
58
0
0
0
15
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _