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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCO2
All Species:
23.94
Human Site:
S246
Identified Species:
47.88
UniProt:
O43819
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43819
NP_005129.2
266
29810
S246
D
Y
Y
G
R
S
R
S
A
E
Q
I
S
D
S
Chimpanzee
Pan troglodytes
XP_001164786
301
33690
R282
D
Y
F
G
Q
N
K
R
K
G
E
I
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001116350
141
16070
A122
Y
Y
G
R
S
K
S
A
E
Q
I
S
D
S
V
Dog
Lupus familis
XP_538308
390
42944
S370
D
Y
Y
G
R
A
A
S
A
Q
Q
I
A
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCL2
255
28925
S235
D
Y
Y
G
R
S
R
S
A
E
Q
I
V
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520199
163
18727
T143
D
Y
Y
G
R
G
K
T
D
E
Q
I
A
D
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001108271
275
31026
T255
D
Y
Y
G
R
G
K
T
D
Q
E
I
A
D
S
Zebra Danio
Brachydanio rerio
Q5RH02
279
32092
N258
D
Y
Y
N
R
M
K
N
D
T
Q
I
A
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608884
251
28157
D226
D
Y
Y
G
Q
N
R
D
K
D
Q
C
V
A
S
Honey Bee
Apis mellifera
XP_001122061
262
30294
T227
D
Y
Y
G
L
T
H
T
A
E
Q
I
V
H
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797763
313
34510
T291
D
Y
Y
G
Q
N
K
T
D
E
Q
V
A
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23833
295
33147
Y260
V
D
A
L
G
R
N
Y
D
E
K
T
G
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
50
56.4
N.A.
78.9
N.A.
N.A.
44.3
N.A.
49
54.1
N.A.
43.2
40.9
N.A.
40.8
Protein Similarity:
100
59.7
52.2
61
N.A.
85.7
N.A.
N.A.
53.3
N.A.
65
65.2
N.A.
62.4
63.9
N.A.
55.5
P-Site Identity:
100
33.3
6.6
66.6
N.A.
86.6
N.A.
N.A.
66.6
N.A.
53.3
46.6
N.A.
46.6
60
N.A.
40
P-Site Similarity:
100
73.3
20
93.3
N.A.
93.3
N.A.
N.A.
86.6
N.A.
86.6
73.3
N.A.
66.6
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
9
34
0
0
0
50
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
84
9
0
0
0
0
0
9
42
9
0
0
9
25
9
% D
% Glu:
0
0
0
0
0
0
0
0
9
50
17
0
0
17
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
75
9
17
0
0
0
9
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
67
0
0
0
% I
% Lys:
0
0
0
0
0
9
42
0
17
0
9
0
0
0
0
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
25
9
9
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
25
0
0
0
0
25
67
0
0
0
0
% Q
% Arg:
0
0
0
9
50
9
25
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
17
9
25
0
0
0
9
9
9
75
% S
% Thr:
0
0
0
0
0
9
0
34
0
9
0
9
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
9
25
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
92
75
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _