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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCO2
All Species:
39.7
Human Site:
T166
Identified Species:
79.39
UniProt:
O43819
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43819
NP_005129.2
266
29810
T166
P
V
Q
P
V
F
I
T
V
D
P
E
R
D
D
Chimpanzee
Pan troglodytes
XP_001164786
301
33690
S202
D
L
T
P
L
F
I
S
I
D
P
E
R
D
T
Rhesus Macaque
Macaca mulatta
XP_001116350
141
16070
V42
V
Q
P
V
F
I
T
V
D
P
E
R
D
D
V
Dog
Lupus familis
XP_538308
390
42944
T290
P
V
Q
P
V
F
I
T
V
D
P
E
R
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCL2
255
28925
T155
L
V
Q
P
V
F
I
T
V
D
P
E
R
D
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520199
163
18727
T63
P
V
Q
P
V
F
V
T
V
D
P
E
R
D
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001108271
275
31026
S175
H
V
L
P
V
F
I
S
I
D
P
E
R
D
S
Zebra Danio
Brachydanio rerio
Q5RH02
279
32092
T178
S
V
Q
P
L
F
I
T
V
D
P
E
R
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608884
251
28157
T146
A
V
Q
P
I
F
I
T
V
D
P
E
R
D
S
Honey Bee
Apis mellifera
XP_001122061
262
30294
S147
K
V
Q
P
I
F
I
S
V
D
P
E
R
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797763
313
34510
S211
K
V
V
P
V
F
I
S
I
D
P
E
R
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23833
295
33147
T180
T
L
Q
P
L
F
I
T
C
D
P
A
R
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
50
56.4
N.A.
78.9
N.A.
N.A.
44.3
N.A.
49
54.1
N.A.
43.2
40.9
N.A.
40.8
Protein Similarity:
100
59.7
52.2
61
N.A.
85.7
N.A.
N.A.
53.3
N.A.
65
65.2
N.A.
62.4
63.9
N.A.
55.5
P-Site Identity:
100
53.3
6.6
93.3
N.A.
93.3
N.A.
N.A.
93.3
N.A.
66.6
86.6
N.A.
80
73.3
N.A.
73.3
P-Site Similarity:
100
80
6.6
93.3
N.A.
93.3
N.A.
N.A.
100
N.A.
80
93.3
N.A.
86.6
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
9
92
0
0
9
100
42
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
84
0
0
0
% E
% Phe:
0
0
0
0
9
92
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
9
84
0
25
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
17
9
0
25
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
0
9
92
0
0
0
0
0
9
92
0
0
0
0
% P
% Gln:
0
9
67
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
92
0
0
% R
% Ser:
9
0
0
0
0
0
0
34
0
0
0
0
0
0
25
% S
% Thr:
9
0
9
0
0
0
9
59
0
0
0
0
0
0
25
% T
% Val:
9
75
9
9
50
0
9
9
59
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _