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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCO2 All Species: 0
Human Site: T9 Identified Species: 0
UniProt: O43819 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43819 NP_005129.2 266 29810 T9 L L L T R S P T A W H R L S Q
Chimpanzee Pan troglodytes XP_001164786 301 33690 R47 L L R Q F C A R Q A E A W R A
Rhesus Macaque Macaca mulatta XP_001116350 141 16070
Dog Lupus familis XP_538308 390 42944 K133 L L L A W A P K P W H R L A H
Cat Felis silvestris
Mouse Mus musculus Q8VCL2 255 28925 W10 L A L G P K A W P K L S Q F K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520199 163 18727
Chicken Gallus gallus
Frog Xenopus laevis NP_001108271 275 31026 L16 F H R A L S S L L T R G A V Q
Zebra Danio Brachydanio rerio Q5RH02 279 32092 I21 W S V L Q S T I R G N N I S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608884 251 28157 A20 R R W A Q Q P A I R H Y A A P
Honey Bee Apis mellifera XP_001122061 262 30294 K22 L K D R S T I K A N K V T L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797763 313 34510 A59 H T C T R G M A S K Q T T T F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23833 295 33147 L10 K L S R S A N L R L V Q L P A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.2 50 56.4 N.A. 78.9 N.A. N.A. 44.3 N.A. 49 54.1 N.A. 43.2 40.9 N.A. 40.8
Protein Similarity: 100 59.7 52.2 61 N.A. 85.7 N.A. N.A. 53.3 N.A. 65 65.2 N.A. 62.4 63.9 N.A. 55.5
P-Site Identity: 100 13.3 0 53.3 N.A. 13.3 N.A. N.A. 0 N.A. 13.3 13.3 N.A. 13.3 13.3 N.A. 13.3
P-Site Similarity: 100 13.3 0 66.6 N.A. 20 N.A. N.A. 0 N.A. 13.3 40 N.A. 26.6 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 25 0 17 17 17 17 9 0 9 17 17 17 % A
% Cys: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % E
% Phe: 9 0 0 0 9 0 0 0 0 0 0 0 0 9 9 % F
% Gly: 0 0 0 9 0 9 0 0 0 9 0 9 0 0 0 % G
% His: 9 9 0 0 0 0 0 0 0 0 25 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 9 9 9 0 0 0 9 0 0 % I
% Lys: 9 9 0 0 0 9 0 17 0 17 9 0 0 0 9 % K
% Leu: 42 34 25 9 9 0 0 17 9 9 9 0 25 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 9 9 9 0 0 9 % N
% Pro: 0 0 0 0 9 0 25 0 17 0 0 0 0 9 9 % P
% Gln: 0 0 0 9 17 9 0 0 9 0 9 9 9 0 17 % Q
% Arg: 9 9 17 17 17 0 0 9 17 9 9 17 0 9 0 % R
% Ser: 0 9 9 0 17 25 9 0 9 0 0 9 0 17 0 % S
% Thr: 0 9 0 17 0 9 9 9 0 9 0 9 17 9 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 9 9 0 9 0 % V
% Trp: 9 0 9 0 9 0 0 9 0 17 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _