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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYAL3
All Species:
4.55
Human Site:
Y167
Identified Species:
14.29
UniProt:
O43820
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43820
NP_003540.2
417
46501
Y167
L
D
P
Q
E
Q
L
Y
K
A
Y
T
G
F
E
Chimpanzee
Pan troglodytes
XP_516476
417
46468
Y167
L
D
P
Q
E
Q
L
Y
K
A
Y
T
G
F
E
Rhesus Macaque
Macaca mulatta
XP_001101134
473
53962
K173
W
P
P
D
R
I
V
K
Q
A
Q
Y
E
F
E
Dog
Lupus familis
XP_850793
430
48398
H167
L
D
P
Q
E
Q
F
H
K
A
R
A
G
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEI3
412
46129
H168
L
D
P
Q
E
Q
L
H
K
A
H
T
S
F
E
Rat
Rattus norvegicus
Q76HM9
412
46188
H168
L
N
P
Q
E
Q
L
H
K
A
Q
T
G
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080777
487
56182
K180
W
P
R
E
Q
V
E
K
E
A
L
Y
D
F
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Q08169
382
44241
V169
K
K
L
S
V
E
V
V
R
R
E
H
P
F
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
39.7
79
N.A.
77.4
79.8
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
N.A.
28.2
N.A.
N.A.
Protein Similarity:
100
100
53.2
84.6
N.A.
83.9
85.8
N.A.
N.A.
N.A.
48.6
N.A.
N.A.
N.A.
45
N.A.
N.A.
P-Site Identity:
100
100
26.6
73.3
N.A.
80
80
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
40
80
N.A.
93.3
93.3
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
88
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
13
0
0
0
0
0
0
0
0
13
0
0
% D
% Glu:
0
0
0
13
63
13
13
0
13
0
13
0
13
0
88
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
0
0
100
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
38
0
0
13
13
0
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
13
0
0
0
0
0
25
63
0
0
0
0
0
0
% K
% Leu:
63
0
13
0
0
0
50
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
25
75
0
0
0
0
0
0
0
0
0
13
0
0
% P
% Gln:
0
0
0
63
13
63
0
0
13
0
25
0
0
0
0
% Q
% Arg:
0
0
13
0
13
0
0
0
13
13
13
0
0
0
0
% R
% Ser:
0
0
0
13
0
0
0
0
0
0
0
0
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% T
% Val:
0
0
0
0
13
13
25
13
0
0
0
0
0
0
0
% V
% Trp:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
25
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _