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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AKAP8 All Species: 10.91
Human Site: S124 Identified Species: 34.29
UniProt: O43823 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43823 NP_005849.1 692 76108 S124 E G I Q D R E S S F R F Q P F
Chimpanzee Pan troglodytes XP_001159349 570 63092 Y69 P V I G Y E N Y N Y Y G A Q N
Rhesus Macaque Macaca mulatta XP_001112993 655 72130 S131 G S F G G Q Y S E C R D P A R
Dog Lupus familis XP_853021 648 71770 D128 Y D S Y E A C D S R A I L S E
Cat Felis silvestris
Mouse Mus musculus Q9DBR0 687 76275 S124 E G V Q D R D S S F R F Q P Y
Rat Rattus norvegicus Q63014 687 76143 S124 E G M Q D R D S S F R F Q P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ02 565 63393 G63 G M E S H G G G G G G G G G G
Frog Xenopus laevis NP_001091313 494 55916
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.7 88.4 33.5 N.A. 79.3 79.6 N.A. N.A. 25.1 28.6 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 69 90.1 49.1 N.A. 86.8 87.4 N.A. N.A. 38.7 39.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 13.3 6.6 N.A. 80 80 N.A. N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 13.3 N.A. 100 100 N.A. N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 0 0 0 0 13 0 13 13 0 % A
% Cys: 0 0 0 0 0 0 13 0 0 13 0 0 0 0 0 % C
% Asp: 0 13 0 0 38 0 25 13 0 0 0 13 0 0 0 % D
% Glu: 38 0 13 0 13 13 13 0 13 0 0 0 0 0 13 % E
% Phe: 0 0 13 0 0 0 0 0 0 38 0 38 0 0 13 % F
% Gly: 25 38 0 25 13 13 13 13 13 13 13 25 13 13 13 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 25 0 0 0 0 0 0 0 0 13 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % L
% Met: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 13 0 13 0 0 0 0 0 13 % N
% Pro: 13 0 0 0 0 0 0 0 0 0 0 0 13 38 0 % P
% Gln: 0 0 0 38 0 13 0 0 0 0 0 0 38 13 0 % Q
% Arg: 0 0 0 0 0 38 0 0 0 13 50 0 0 0 13 % R
% Ser: 0 13 13 13 0 0 0 50 50 0 0 0 0 13 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 13 13 0 13 13 0 13 13 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _