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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP8
All Species:
10.91
Human Site:
S124
Identified Species:
34.29
UniProt:
O43823
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43823
NP_005849.1
692
76108
S124
E
G
I
Q
D
R
E
S
S
F
R
F
Q
P
F
Chimpanzee
Pan troglodytes
XP_001159349
570
63092
Y69
P
V
I
G
Y
E
N
Y
N
Y
Y
G
A
Q
N
Rhesus Macaque
Macaca mulatta
XP_001112993
655
72130
S131
G
S
F
G
G
Q
Y
S
E
C
R
D
P
A
R
Dog
Lupus familis
XP_853021
648
71770
D128
Y
D
S
Y
E
A
C
D
S
R
A
I
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR0
687
76275
S124
E
G
V
Q
D
R
D
S
S
F
R
F
Q
P
Y
Rat
Rattus norvegicus
Q63014
687
76143
S124
E
G
M
Q
D
R
D
S
S
F
R
F
Q
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ02
565
63393
G63
G
M
E
S
H
G
G
G
G
G
G
G
G
G
G
Frog
Xenopus laevis
NP_001091313
494
55916
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.7
88.4
33.5
N.A.
79.3
79.6
N.A.
N.A.
25.1
28.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69
90.1
49.1
N.A.
86.8
87.4
N.A.
N.A.
38.7
39.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
6.6
N.A.
80
80
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
13.3
N.A.
100
100
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
0
0
0
13
0
13
13
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
13
0
0
0
0
0
% C
% Asp:
0
13
0
0
38
0
25
13
0
0
0
13
0
0
0
% D
% Glu:
38
0
13
0
13
13
13
0
13
0
0
0
0
0
13
% E
% Phe:
0
0
13
0
0
0
0
0
0
38
0
38
0
0
13
% F
% Gly:
25
38
0
25
13
13
13
13
13
13
13
25
13
13
13
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
0
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% L
% Met:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
13
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
13
38
0
% P
% Gln:
0
0
0
38
0
13
0
0
0
0
0
0
38
13
0
% Q
% Arg:
0
0
0
0
0
38
0
0
0
13
50
0
0
0
13
% R
% Ser:
0
13
13
13
0
0
0
50
50
0
0
0
0
13
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
13
13
0
13
13
0
13
13
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _