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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AKAP8 All Species: 8.48
Human Site: S353 Identified Species: 26.67
UniProt: O43823 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43823 NP_005849.1 692 76108 S353 G E D E L C D S G R Q R G E K
Chimpanzee Pan troglodytes XP_001159349 570 63092 Q288 E E I Q K H L Q S K F H K E T
Rhesus Macaque Macaca mulatta XP_001112993 655 72130 A354 A A D R I Q F A C S V C K F R
Dog Lupus familis XP_853021 648 71770 R362 D D S G Q I K R K L Q A G K K
Cat Felis silvestris
Mouse Mus musculus Q9DBR0 687 76275 S350 G E D D L C D S R K Q R G E K
Rat Rattus norvegicus Q63014 687 76143 S351 G E D D L C D S R K Q R G E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ02 565 63393 D282 N M K S S F Q D S T I E E I E
Frog Xenopus laevis NP_001091313 494 55916 F212 P P F K P V G F F G K K Q K L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.7 88.4 33.5 N.A. 79.3 79.6 N.A. N.A. 25.1 28.6 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 69 90.1 49.1 N.A. 86.8 87.4 N.A. N.A. 38.7 39.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 20 N.A. 80 80 N.A. N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 26.6 33.3 N.A. 93.3 93.3 N.A. N.A. 6.6 26.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 0 0 0 0 0 13 0 0 0 13 0 0 0 % A
% Cys: 0 0 0 0 0 38 0 0 13 0 0 13 0 0 0 % C
% Asp: 13 13 50 25 0 0 38 13 0 0 0 0 0 0 0 % D
% Glu: 13 50 0 13 0 0 0 0 0 0 0 13 13 50 13 % E
% Phe: 0 0 13 0 0 13 13 13 13 0 13 0 0 13 0 % F
% Gly: 38 0 0 13 0 0 13 0 13 13 0 0 50 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 13 0 0 0 % H
% Ile: 0 0 13 0 13 13 0 0 0 0 13 0 0 13 0 % I
% Lys: 0 0 13 13 13 0 13 0 13 38 13 13 25 25 50 % K
% Leu: 0 0 0 0 38 0 13 0 0 13 0 0 0 0 13 % L
% Met: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 13 0 0 13 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 13 13 13 13 13 0 0 50 0 13 0 0 % Q
% Arg: 0 0 0 13 0 0 0 13 25 13 0 38 0 0 13 % R
% Ser: 0 0 13 13 13 0 0 38 25 13 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 13 % T
% Val: 0 0 0 0 0 13 0 0 0 0 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _