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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3B
All Species:
36.36
Human Site:
S93
Identified Species:
61.54
UniProt:
O43837
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43837
NP_008830.2
385
42184
S93
S
E
V
Q
N
M
A
S
E
E
K
L
E
Q
V
Chimpanzee
Pan troglodytes
XP_001157460
385
42195
S93
S
E
V
Q
N
M
A
S
E
E
K
L
E
Q
V
Rhesus Macaque
Macaca mulatta
XP_001114288
385
42236
S93
S
E
V
Q
N
M
A
S
E
E
K
L
E
Q
V
Dog
Lupus familis
XP_534367
385
42314
S93
S
E
V
Q
N
M
A
S
E
E
K
L
E
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
P70404
393
42767
D96
V
H
V
S
S
N
A
D
E
E
D
I
R
N
A
Rat
Rattus norvegicus
Q68FX0
385
42335
S93
S
E
V
Q
N
M
A
S
E
E
K
L
E
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026558
385
42312
S92
S
E
V
Q
N
M
A
S
E
E
K
L
D
Q
V
Frog
Xenopus laevis
NP_001085395
376
41736
S88
S
E
V
Q
N
M
A
S
K
E
K
L
E
Q
V
Zebra Danio
Brachydanio rerio
NP_001002157
382
41838
S93
S
E
V
Q
N
M
A
S
E
E
K
L
N
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
K93
P
V
R
G
P
D
G
K
F
G
I
P
Q
A
A
Honey Bee
Apis mellifera
XP_624511
374
40935
S86
S
E
V
N
P
T
L
S
A
P
L
E
Q
V
S
Nematode Worm
Caenorhab. elegans
Q93353
379
41534
S87
S
E
V
H
Y
T
R
S
S
S
I
E
N
A
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93032
367
39572
M78
P
F
E
V
H
G
D
M
K
S
L
P
E
G
L
Baker's Yeast
Sacchar. cerevisiae
P28834
360
39306
S80
G
V
Y
E
A
V
E
S
L
K
R
N
K
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
96
N.A.
48.5
94
N.A.
N.A.
84.1
79.4
78.6
N.A.
38.9
57.9
57.1
N.A.
Protein Similarity:
100
99.7
98.9
97.4
N.A.
64.3
96.6
N.A.
N.A.
90.6
87.2
85.7
N.A.
60.7
72.9
71.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
26.6
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
0
26.6
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
N.A.
100
100
93.3
N.A.
6.6
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.9
45.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
65
0
8
0
0
0
0
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
8
0
0
8
0
8
0
0
% D
% Glu:
0
72
8
8
0
0
8
0
58
65
0
15
50
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
8
8
0
0
8
0
0
0
8
8
% G
% His:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
15
8
58
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
8
0
15
58
0
0
8
% L
% Met:
0
0
0
0
0
58
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
58
8
0
0
0
0
0
8
15
8
0
% N
% Pro:
15
0
0
0
15
0
0
0
0
8
0
15
0
0
0
% P
% Gln:
0
0
0
58
0
0
0
0
0
0
0
0
15
50
0
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% R
% Ser:
72
0
0
8
8
0
0
79
8
15
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% T
% Val:
8
15
79
8
0
8
0
0
0
0
0
0
0
8
65
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _