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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3B
All Species:
53.03
Human Site:
T167
Identified Species:
89.74
UniProt:
O43837
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43837
NP_008830.2
385
42184
T167
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Chimpanzee
Pan troglodytes
XP_001157460
385
42195
T167
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001114288
385
42236
T167
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Dog
Lupus familis
XP_534367
385
42314
T167
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P70404
393
42767
T170
I
L
I
V
R
E
N
T
E
G
E
Y
S
S
L
Rat
Rattus norvegicus
Q68FX0
385
42335
T167
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026558
385
42312
T166
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Frog
Xenopus laevis
NP_001085395
376
41736
T162
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Zebra Danio
Brachydanio rerio
NP_001002157
382
41838
T167
L
V
I
I
R
E
Q
T
E
G
E
Y
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
T165
V
V
T
I
R
E
N
T
E
G
E
Y
S
G
I
Honey Bee
Apis mellifera
XP_624511
374
40935
T160
C
I
I
I
R
E
Q
T
E
G
E
Y
S
A
L
Nematode Worm
Caenorhab. elegans
Q93353
379
41534
T164
F
V
I
V
R
E
Q
T
E
G
E
Y
S
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93032
367
39572
T150
I
V
V
I
R
E
N
T
E
G
E
Y
A
G
L
Baker's Yeast
Sacchar. cerevisiae
P28834
360
39306
S154
F
S
G
L
E
H
E
S
V
P
G
V
V
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
96
N.A.
48.5
94
N.A.
N.A.
84.1
79.4
78.6
N.A.
38.9
57.9
57.1
N.A.
Protein Similarity:
100
99.7
98.9
97.4
N.A.
64.3
96.6
N.A.
N.A.
90.6
87.2
85.7
N.A.
60.7
72.9
71.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
73.3
100
N.A.
N.A.
100
100
100
N.A.
66.6
80
86.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
100
100
100
N.A.
80
93.3
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.9
45.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
93
8
0
93
0
93
0
0
8
0
% E
% Phe:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
93
8
0
0
15
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
8
79
79
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
58
8
0
8
0
0
0
0
0
0
0
0
0
0
86
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
8
0
0
0
0
86
72
8
% S
% Thr:
0
0
8
0
0
0
0
93
0
0
0
0
0
0
0
% T
% Val:
8
79
8
15
0
0
0
0
8
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _