KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDH3B
All Species:
33.33
Human Site:
Y128
Identified Species:
56.41
UniProt:
O43837
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43837
NP_008830.2
385
42184
Y128
Y
K
G
E
L
A
S
Y
D
M
R
L
R
R
K
Chimpanzee
Pan troglodytes
XP_001157460
385
42195
Y128
Y
K
G
E
L
A
S
Y
D
M
R
L
R
R
K
Rhesus Macaque
Macaca mulatta
XP_001114288
385
42236
Y128
Y
K
G
E
L
A
S
Y
D
M
R
L
R
R
K
Dog
Lupus familis
XP_534367
385
42314
Y128
Y
K
G
E
L
A
S
Y
D
M
R
L
R
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P70404
393
42767
R131
L
P
P
S
H
K
S
R
N
N
I
L
R
T
S
Rat
Rattus norvegicus
Q68FX0
385
42335
Y128
Y
K
G
E
L
A
S
Y
D
M
Q
L
R
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026558
385
42312
Y127
Y
K
G
E
L
A
S
Y
D
M
R
L
R
R
K
Frog
Xenopus laevis
NP_001085395
376
41736
Y123
Y
K
G
E
L
A
S
Y
E
M
R
L
R
R
K
Zebra Danio
Brachydanio rerio
NP_001002157
382
41838
Y128
Y
K
G
E
L
A
S
Y
E
M
R
L
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWH4
377
40826
L128
K
G
H
R
S
L
N
L
A
L
R
K
E
F
N
Honey Bee
Apis mellifera
XP_624511
374
40935
L121
H
T
G
E
L
Q
T
L
N
M
K
L
R
K
S
Nematode Worm
Caenorhab. elegans
Q93353
379
41534
Q122
L
H
T
E
G
E
L
Q
G
L
N
M
R
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93032
367
39572
V113
G
G
V
S
S
L
N
V
N
L
R
K
E
L
D
Baker's Yeast
Sacchar. cerevisiae
P28834
360
39306
Y115
L
R
K
Q
L
D
I
Y
A
N
V
A
L
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
96
N.A.
48.5
94
N.A.
N.A.
84.1
79.4
78.6
N.A.
38.9
57.9
57.1
N.A.
Protein Similarity:
100
99.7
98.9
97.4
N.A.
64.3
96.6
N.A.
N.A.
90.6
87.2
85.7
N.A.
60.7
72.9
71.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
100
93.3
93.3
N.A.
6.6
40
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
N.A.
100
100
100
N.A.
20
73.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.9
45.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
58
0
0
15
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
43
0
0
0
0
0
8
% D
% Glu:
0
0
0
72
0
8
0
0
15
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
8
15
65
0
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
8
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% I
% Lys:
8
58
8
0
0
8
0
0
0
0
8
15
0
8
65
% K
% Leu:
22
0
0
0
72
15
8
15
0
22
0
72
8
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
65
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
22
15
8
0
0
0
8
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
65
0
79
58
8
% R
% Ser:
0
0
0
15
15
0
65
0
0
0
0
0
0
0
15
% S
% Thr:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
58
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _