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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRD1 All Species: 22.73
Human Site: S1079 Identified Species: 41.67
UniProt: O43847 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43847 NP_001095132.1 1150 131572 S1079 K A H R G P G S K M L S V H V
Chimpanzee Pan troglodytes XP_001140946 1151 131624 S1080 K A H R G P G S K M L S V H V
Rhesus Macaque Macaca mulatta XP_001105075 1237 141727 S1166 K A H R G P G S K M L S V H V
Dog Lupus familis XP_859649 1159 132371 S1089 K A H R G P G S K M L S V H V
Cat Felis silvestris
Mouse Mus musculus Q8BHG1 1161 132873 S1091 K A H R G P G S K M L S V H V
Rat Rattus norvegicus P47245 1161 132957 S1091 K A H R G P G S K M L S V H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509651 859 96644 Q789 R R P P P N G Q E P D P G G G
Chicken Gallus gallus NP_001026455 1158 132212 E1087 H A H R S S K E K V L S V H V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694205 1091 124552 N1015 M E H R G E G N R K L S V H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22817 990 113666 K920 Y F K K F I A K D G E E R R V
Honey Bee Apis mellifera XP_624437 1061 122950 N988 Q S H T I N G N N F R K L S V
Nematode Worm Caenorhab. elegans Q10040 856 98243 A786 D F D Y Q V W A M F K E N P P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06010 1027 117560 N957 E N Y I M S E N A S K L I L H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 84.3 94.1 N.A. 92.4 92.3 N.A. 47.4 76 N.A. 68.3 N.A. 29.1 38.7 25.1 N.A.
Protein Similarity: 100 99.8 85.9 96.7 N.A. 95.2 95.1 N.A. 54.6 85.7 N.A. 81.9 N.A. 47.8 58.8 42.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 60 N.A. 60 N.A. 6.6 20 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 66.6 N.A. 73.3 N.A. 13.3 46.6 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 0 0 0 0 8 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 0 0 8 0 8 0 0 0 0 % D
% Glu: 8 8 0 0 0 8 8 8 8 0 8 16 0 0 0 % E
% Phe: 0 16 0 0 8 0 0 0 0 16 0 0 0 0 0 % F
% Gly: 0 0 0 0 54 0 70 0 0 8 0 0 8 8 8 % G
% His: 8 0 70 0 0 0 0 0 0 0 0 0 0 62 8 % H
% Ile: 0 0 0 8 8 8 0 0 0 0 0 0 8 0 0 % I
% Lys: 47 0 8 8 0 0 8 8 54 8 16 8 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 62 8 8 8 0 % L
% Met: 8 0 0 0 8 0 0 0 8 47 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 16 0 24 8 0 0 0 8 0 0 % N
% Pro: 0 0 8 8 8 47 0 0 0 8 0 8 0 8 8 % P
% Gln: 8 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 62 0 0 0 0 8 0 8 0 8 8 0 % R
% Ser: 0 8 0 0 8 16 0 47 0 8 0 62 0 8 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 8 0 0 62 0 77 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _