Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRD1 All Species: 31.52
Human Site: T1029 Identified Species: 57.78
UniProt: O43847 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43847 NP_001095132.1 1150 131572 T1029 K L K E C E D T H L G E E V D
Chimpanzee Pan troglodytes XP_001140946 1151 131624 T1030 K L K E C E D T H L G E E V D
Rhesus Macaque Macaca mulatta XP_001105075 1237 141727 T1116 K L K E C E D T H L G E E V D
Dog Lupus familis XP_859649 1159 132371 T1039 K L K E C E D T H L G E E V D
Cat Felis silvestris
Mouse Mus musculus Q8BHG1 1161 132873 T1041 K L K E C E D T H L G E E V D
Rat Rattus norvegicus P47245 1161 132957 T1041 K L K E C E D T H L G E E V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509651 859 96644 I739 A Y I R F H L I S P L V Q Q S
Chicken Gallus gallus NP_001026455 1158 132212 S1037 K L K E C E D S H L G E E V D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694205 1091 124552 T965 K L K G C E D T H L G E E V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22817 990 113666 K870 L A V K K L E K P K T I F Q Q
Honey Bee Apis mellifera XP_624437 1061 122950 I938 K L K Q C A D I H L K E E V D
Nematode Worm Caenorhab. elegans Q10040 856 98243 R736 Y N V S T E S R L N D G N V Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06010 1027 117560 K907 N S L L Q K F K N M A E E S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 84.3 94.1 N.A. 92.4 92.3 N.A. 47.4 76 N.A. 68.3 N.A. 29.1 38.7 25.1 N.A.
Protein Similarity: 100 99.8 85.9 96.7 N.A. 95.2 95.1 N.A. 54.6 85.7 N.A. 81.9 N.A. 47.8 58.8 42.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 93.3 N.A. 93.3 N.A. 0 73.3 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 N.A. 93.3 N.A. 13.3 80 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 0 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 70 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 70 0 0 0 8 0 0 0 70 % D
% Glu: 0 0 0 54 0 70 8 0 0 0 0 77 77 0 0 % E
% Phe: 0 0 0 0 8 0 8 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 62 8 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 70 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 16 0 0 0 8 0 0 0 % I
% Lys: 70 0 70 8 8 8 0 16 0 8 8 0 0 0 0 % K
% Leu: 8 70 8 8 0 8 8 0 8 70 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 8 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 0 0 0 0 0 8 16 8 % Q
% Arg: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 8 0 0 8 8 8 0 0 0 0 8 8 % S
% Thr: 0 0 0 0 8 0 0 54 0 0 8 0 0 0 0 % T
% Val: 0 0 16 0 0 0 0 0 0 0 0 8 0 77 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _