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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALU All Species: 20.61
Human Site: S78 Identified Species: 45.33
UniProt: O43852 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43852 NP_001124146.1 315 37107 S78 E R L G K I V S K I D G D K D
Chimpanzee Pan troglodytes XP_522670 331 38672 D89 E R L G K I V D R I D N D G D
Rhesus Macaque Macaca mulatta XP_001091280 319 37387 S78 E R L G K I V S K I D G D K D
Dog Lupus familis XP_849335 315 37059 S78 E R L G K I V S K I D G D K D
Cat Felis silvestris
Mouse Mus musculus O35887 315 37045 S78 E R L G K I V S K I D D D K D
Rat Rattus norvegicus O35783 315 36978 D78 E K L G M I V D K I D T D K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509670 315 37119 S78 E R L G K I V S K I D E D K D
Chicken Gallus gallus Q5ZKE5 356 41889 S102 K K L M V I F S K V D I D N D
Frog Xenopus laevis Q6IP82 315 37037 G78 E R L G M I V G K I D L D N D
Zebra Danio Brachydanio rerio Q7SXV9 315 37316 E78 E R L G K I V E K I D E D H D
Tiger Blowfish Takifugu rubipres O93434 322 38188 D80 D R L S K I V D R I D G D G N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.7 98.7 99.3 N.A. 98 88.5 N.A. 96.1 28 80.9 76.8 59.6 N.A. N.A. N.A. N.A.
Protein Similarity: 100 75.2 98.7 99.6 N.A. 99 94.5 N.A. 98.7 51.4 90.1 87.9 77.3 N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 100 100 N.A. 93.3 73.3 N.A. 93.3 46.6 73.3 80 60 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 100 100 N.A. 93.3 80 N.A. 93.3 66.6 73.3 80 80 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 28 0 0 100 10 100 0 91 % D
% Glu: 82 0 0 0 0 0 0 10 0 0 0 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 82 0 0 0 10 0 0 0 37 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 100 0 0 0 91 0 10 0 0 0 % I
% Lys: 10 19 0 0 73 0 0 0 82 0 0 0 0 55 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 10 19 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 19 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 82 0 0 0 0 0 0 19 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 0 55 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 10 0 91 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _