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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9B All Species: 31.82
Human Site: S1138 Identified Species: 58.33
UniProt: O43861 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43861 NP_940933.3 1147 129304 S1138 K Y L R R K L S P P S Y C K L
Chimpanzee Pan troglodytes XP_001143568 1108 125190 S1099 K Y L R R K L S P P S Y C K L
Rhesus Macaque Macaca mulatta XP_001087804 1147 129161 S1138 K Y L R R K L S P P S Y C K L
Dog Lupus familis XP_855968 1147 129093 L1137 L K Y L K R K L S P P S Y S K
Cat Felis silvestris
Mouse Mus musculus P98195 1146 128999 S1137 K Y L K R K L S P P S Y S K L
Rat Rattus norvegicus NP_001099600 1147 129160 S1138 K Y L K R K L S P P S Y S K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509503 1195 134451 S1186 K Y L K R K L S P P S Y S K L
Chicken Gallus gallus XP_417508 1115 125396 P1107 Y L R R R F S P P S Y S K L T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 S1099 K Y L K R K F S P P S Y S K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 S1268 K F L R K K F S P P S Y T K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 P1097 F L R R R F S P P S Y S K L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 S1096 Q S Q S R L S S S S G Y T R N
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 Y1142 R R L H P P S Y A K V Q E F A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 98.5 92.5 N.A. 93.2 93 N.A. 87.1 70 N.A. 81.7 N.A. N.A. 55.6 N.A. 60.7
Protein Similarity: 100 96.4 99.3 96.4 N.A. 97 97.1 N.A. 91.8 81.3 N.A. 88.9 N.A. N.A. 70.9 N.A. 76.8
P-Site Identity: 100 100 100 6.6 N.A. 86.6 86.6 N.A. 86.6 20 N.A. 80 N.A. N.A. 73.3 N.A. 20
P-Site Similarity: 100 100 100 20 N.A. 93.3 93.3 N.A. 93.3 20 N.A. 86.6 N.A. N.A. 86.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 29 47 N.A.
Protein Similarity: N.A. N.A. N.A. 46.9 65 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 8 8 0 0 0 16 16 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 62 8 0 31 16 62 8 0 0 8 0 0 16 62 8 % K
% Leu: 8 16 70 8 0 8 47 8 0 0 0 0 0 16 62 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 8 8 0 16 77 70 8 0 0 0 0 % P
% Gln: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 8 16 47 77 8 0 0 0 0 0 0 0 8 0 % R
% Ser: 0 8 0 8 0 0 31 70 16 24 62 24 31 8 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 54 8 0 0 0 0 8 0 0 16 70 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _