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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9B All Species: 26.67
Human Site: S328 Identified Species: 48.89
UniProt: O43861 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43861 NP_940933.3 1147 129304 S328 S D P P I H E S L S I E N T L
Chimpanzee Pan troglodytes XP_001143568 1108 125190 V307 T I V A S G T V I G V V I Y T
Rhesus Macaque Macaca mulatta XP_001087804 1147 129161 S328 S D P P V H E S L S I E N T L
Dog Lupus familis XP_855968 1147 129093 S327 C D P P I H E S L S I E N T L
Cat Felis silvestris
Mouse Mus musculus P98195 1146 128999 S327 S D P P I H E S L S I E N T L
Rat Rattus norvegicus NP_001099600 1147 129160 S328 S D P P I H E S L S I E N T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509503 1195 134451 S372 S D P P I H E S L S I E N T L
Chicken Gallus gallus XP_417508 1115 125396 S319 S D P S V N E S L S I E N T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 L305 S L S I E N T L W A S T V V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 L460 G Y S S E E S L G V D N T L W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 A309 E G V S T Q D A L G I E N T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 E306 W Y V Q Y P E E A P W Y E L L
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 Q323 R V A C P L T Q N L S E N D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 98.5 92.5 N.A. 93.2 93 N.A. 87.1 70 N.A. 81.7 N.A. N.A. 55.6 N.A. 60.7
Protein Similarity: 100 96.4 99.3 96.4 N.A. 97 97.1 N.A. 91.8 81.3 N.A. 88.9 N.A. N.A. 70.9 N.A. 76.8
P-Site Identity: 100 0 93.3 93.3 N.A. 100 100 N.A. 100 80 N.A. 6.6 N.A. N.A. 0 N.A. 40
P-Site Similarity: 100 20 100 93.3 N.A. 100 100 N.A. 100 93.3 N.A. 20 N.A. N.A. 0 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 29 47 N.A.
Protein Similarity: N.A. N.A. N.A. 46.9 65 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 8 8 8 0 0 0 0 8 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 54 0 0 0 0 8 0 0 0 8 0 0 8 0 % D
% Glu: 8 0 0 0 16 8 62 8 0 0 0 70 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 0 0 8 0 0 8 16 0 0 0 0 0 % G
% His: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 39 0 0 0 8 0 62 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 0 8 0 16 62 8 0 0 0 16 77 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 16 0 0 8 0 0 8 70 0 0 % N
% Pro: 0 0 54 47 8 8 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 54 0 16 24 8 0 8 54 0 54 16 0 0 0 0 % S
% Thr: 8 0 0 0 8 0 24 0 0 0 0 8 8 62 8 % T
% Val: 0 8 24 0 16 0 0 8 0 8 8 8 8 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 8 0 8 0 0 0 8 % W
% Tyr: 0 16 0 0 8 0 0 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _