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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9B All Species: 20.91
Human Site: S536 Identified Species: 38.33
UniProt: O43861 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43861 NP_940933.3 1147 129304 S536 S A P K V R K S V S S R I H E
Chimpanzee Pan troglodytes XP_001143568 1108 125190 H513 V K A I V L C H N V T P V Y E
Rhesus Macaque Macaca mulatta XP_001087804 1147 129161 S536 S A P K V R K S V S S R I H E
Dog Lupus familis XP_855968 1147 129093 S535 S A P K V R K S V S S R V H E
Cat Felis silvestris
Mouse Mus musculus P98195 1146 128999 S535 S T P K V K K S V S S R I H E
Rat Rattus norvegicus NP_001099600 1147 129160 S536 S T P K V K K S V S S R I H E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509503 1195 134451 P580 R R T Q T P A P K V R R S V S
Chicken Gallus gallus XP_417508 1115 125396 A527 M S S R V H E A V K A I A L C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 R511 V R K S V S S R I H E A V K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 A667 E S T R I Y D A V H A L A L C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 S517 V V T R V F E S V R A L A L C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 D513 R M S V V V K D C Q N G K I I
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 S543 Y V Q S L V S S K N D S L N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 98.5 92.5 N.A. 93.2 93 N.A. 87.1 70 N.A. 81.7 N.A. N.A. 55.6 N.A. 60.7
Protein Similarity: 100 96.4 99.3 96.4 N.A. 97 97.1 N.A. 91.8 81.3 N.A. 88.9 N.A. N.A. 70.9 N.A. 76.8
P-Site Identity: 100 13.3 100 93.3 N.A. 86.6 86.6 N.A. 6.6 13.3 N.A. 6.6 N.A. N.A. 6.6 N.A. 20
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 93.3 N.A. 13.3 46.6 N.A. 20 N.A. N.A. 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 29 47 N.A.
Protein Similarity: N.A. N.A. N.A. 46.9 65 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 0 0 0 8 16 0 0 24 8 24 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 24 % C
% Asp: 0 0 0 0 0 0 8 8 0 0 8 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 16 0 0 0 8 0 0 0 47 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 8 0 8 0 16 0 0 0 39 0 % H
% Ile: 0 0 0 8 8 0 0 0 8 0 0 8 31 8 8 % I
% Lys: 0 8 8 39 0 16 47 0 16 8 0 0 8 8 0 % K
% Leu: 0 0 0 0 8 8 0 0 0 0 0 16 8 24 0 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 8 8 0 0 8 8 % N
% Pro: 0 0 39 0 0 8 0 8 0 0 0 8 0 0 0 % P
% Gln: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 16 16 0 24 0 24 0 8 0 8 8 47 0 0 0 % R
% Ser: 39 16 16 16 0 8 16 54 0 39 39 8 8 0 8 % S
% Thr: 0 16 24 0 8 0 0 0 0 0 8 0 0 0 0 % T
% Val: 24 16 0 8 77 16 0 0 62 16 0 0 24 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _