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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP9B
All Species:
33.64
Human Site:
T494
Identified Species:
61.67
UniProt:
O43861
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43861
NP_940933.3
1147
129304
T494
T
V
S
Y
G
A
D
T
M
D
E
I
Q
S
H
Chimpanzee
Pan troglodytes
XP_001143568
1108
125190
Q471
R
D
S
Y
S
Q
M
Q
S
Q
A
G
G
N
N
Rhesus Macaque
Macaca mulatta
XP_001087804
1147
129161
T494
T
V
S
Y
G
A
D
T
M
D
E
I
Q
S
H
Dog
Lupus familis
XP_855968
1147
129093
T493
T
V
S
Y
G
A
D
T
M
D
E
I
Q
N
H
Cat
Felis silvestris
Mouse
Mus musculus
P98195
1146
128999
T493
T
V
S
Y
G
T
D
T
M
D
E
I
Q
S
H
Rat
Rattus norvegicus
NP_001099600
1147
129160
T494
T
V
S
Y
G
T
D
T
M
D
E
I
Q
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509503
1195
134451
T538
T
V
S
Y
G
T
D
T
M
D
E
I
Q
N
H
Chicken
Gallus gallus
XP_417508
1115
125396
S485
T
V
A
Y
G
L
D
S
M
D
E
V
Q
S
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038619
1108
125101
Q469
T
D
T
M
D
E
I
Q
S
H
I
I
Q
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396589
1276
146194
T625
M
I
S
Y
G
Q
E
T
F
D
E
V
M
T
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799223
1105
125600
S475
T
V
A
F
G
S
D
S
L
D
D
V
K
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P98205
1107
124818
M471
I
A
A
S
K
L
H
M
V
F
V
G
K
N
A
Baker's Yeast
Sacchar. cerevisiae
P40527
1151
130199
L501
L
G
R
I
E
Y
L
L
S
D
K
T
G
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
98.5
92.5
N.A.
93.2
93
N.A.
87.1
70
N.A.
81.7
N.A.
N.A.
55.6
N.A.
60.7
Protein Similarity:
100
96.4
99.3
96.4
N.A.
97
97.1
N.A.
91.8
81.3
N.A.
88.9
N.A.
N.A.
70.9
N.A.
76.8
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
86.6
73.3
N.A.
26.6
N.A.
N.A.
40
N.A.
40
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
40
N.A.
N.A.
66.6
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.9
65
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
0
0
24
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
8
0
62
0
0
77
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
8
8
0
0
0
62
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
70
0
0
0
0
0
0
16
16
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
62
% H
% Ile:
8
8
0
8
0
0
8
0
0
0
8
54
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
8
0
16
0
0
% K
% Leu:
8
0
0
0
0
16
8
8
8
0
0
0
0
0
8
% L
% Met:
8
0
0
8
0
0
8
8
54
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
0
16
0
8
0
0
62
0
0
% Q
% Arg:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
62
8
8
8
0
16
24
0
0
0
0
47
0
% S
% Thr:
70
0
8
0
0
24
0
54
0
0
0
8
0
24
0
% T
% Val:
0
62
0
0
0
0
0
0
8
0
8
24
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
70
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _