Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9B All Species: 27.88
Human Site: Y1132 Identified Species: 51.11
UniProt: O43861 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43861 NP_940933.3 1147 129304 Y1132 L P L Y V L K Y L R R K L S P
Chimpanzee Pan troglodytes XP_001143568 1108 125190 Y1093 L P L Y V P K Y L R R K L S P
Rhesus Macaque Macaca mulatta XP_001087804 1147 129161 Y1132 L P L Y V L K Y L R R K L S P
Dog Lupus familis XP_855968 1147 129093 K1131 C L P L Y V L K Y L K R K L S
Cat Felis silvestris
Mouse Mus musculus P98195 1146 128999 Y1131 L P L Y V L K Y L K R K L S P
Rat Rattus norvegicus NP_001099600 1147 129160 Y1132 L P L Y V L K Y L K R K L S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509503 1195 134451 Y1180 L P L Y V L K Y L K R K L S P
Chicken Gallus gallus XP_417508 1115 125396 L1101 P L Y V L K Y L R R R F S P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 Y1093 L P L Y I I K Y L K R K F S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 F1262 M P L Y I L K F L R K K F S P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 L1091 P L Y I L K F L R R R F S P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 S1090 T P F E F F Q S Q S R L S S S
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 R1136 T A K A I Y R R L H P P S Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 98.5 92.5 N.A. 93.2 93 N.A. 87.1 70 N.A. 81.7 N.A. N.A. 55.6 N.A. 60.7
Protein Similarity: 100 96.4 99.3 96.4 N.A. 97 97.1 N.A. 91.8 81.3 N.A. 88.9 N.A. N.A. 70.9 N.A. 76.8
P-Site Identity: 100 93.3 100 0 N.A. 93.3 93.3 N.A. 93.3 20 N.A. 73.3 N.A. N.A. 66.6 N.A. 20
P-Site Similarity: 100 93.3 100 20 N.A. 100 100 N.A. 100 26.6 N.A. 93.3 N.A. N.A. 93.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 29 47 N.A.
Protein Similarity: N.A. N.A. N.A. 46.9 65 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 8 8 8 8 0 0 0 16 16 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 24 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 16 62 8 0 31 16 62 8 0 0 % K
% Leu: 54 24 62 8 16 47 8 16 70 8 0 8 47 8 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 70 8 0 0 8 0 0 0 0 8 8 0 16 77 % P
% Gln: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 8 16 47 77 8 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 8 0 8 0 0 31 70 16 % S
% Thr: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 47 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 62 8 8 8 54 8 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _