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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC28A2 All Species: 4.55
Human Site: S59 Identified Species: 11.11
UniProt: O43868 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43868 NP_004203.2 658 71926 S59 P S T Y Q R R S R W P F S K A
Chimpanzee Pan troglodytes XP_510372 658 71903 S59 P S T Y Q R R S R W P F S K A
Rhesus Macaque Macaca mulatta XP_001111449 658 72107 R59 P S T H Q R R R Q W P F S K A
Dog Lupus familis XP_852022 753 82237 L166 P F S G W R S L Q P A L R A T
Cat Felis silvestris
Mouse Mus musculus O88627 660 72952 I61 S S L W S R R I F Q P F T K A
Rat Rattus norvegicus Q62773 659 72597 I60 H S S L W R R I L Q P F T K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518475 658 71847 C58 W I L V G L G C A G Y A A Y L
Chicken Gallus gallus XP_413724 662 72480 A61 V A L Y C R K A L R P A S K A
Frog Xenopus laevis NP_001086782 645 70715 K57 Q F V K K H R K I L K Y I G I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001176530 661 72279 R64 T L P A S T P R K P G Y D V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.8 53.2 N.A. 79.8 80.8 N.A. 67 58.3 58.2 N.A. N.A. N.A. N.A. N.A. 45
Protein Similarity: 100 99.6 96.6 66.6 N.A. 87.8 87.7 N.A. 80.4 73.7 74.4 N.A. N.A. N.A. N.A. N.A. 63
P-Site Identity: 100 100 80 13.3 N.A. 46.6 46.6 N.A. 0 40 6.6 N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 26.6 N.A. 60 60 N.A. 6.6 60 20 N.A. N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 0 10 10 0 10 20 10 10 60 % A
% Cys: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 20 0 0 0 0 0 0 10 0 0 50 0 0 0 % F
% Gly: 0 0 0 10 10 0 10 0 0 10 10 0 0 10 0 % G
% His: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 20 10 0 0 0 10 0 10 % I
% Lys: 0 0 0 10 10 0 10 10 10 0 10 0 0 60 0 % K
% Leu: 0 10 30 10 0 10 0 10 20 10 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 40 0 10 0 0 0 10 0 0 20 60 0 0 0 0 % P
% Gln: 10 0 0 0 30 0 0 0 20 20 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 70 60 20 20 10 0 0 10 0 0 % R
% Ser: 10 50 20 0 20 0 10 20 0 0 0 0 40 0 0 % S
% Thr: 10 0 30 0 0 10 0 0 0 0 0 0 20 0 10 % T
% Val: 10 0 10 10 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 10 0 0 10 20 0 0 0 0 30 0 0 0 0 0 % W
% Tyr: 0 0 0 30 0 0 0 0 0 0 10 20 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _