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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
6.36
Human Site:
S120
Identified Species:
14
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
S120
F
P
F
A
E
S
E
S
C
R
K
E
G
T
Q
Chimpanzee
Pan troglodytes
XP_524059
461
49123
P169
C
A
E
K
P
A
D
P
V
D
L
S
P
R
C
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
T106
R
K
E
G
T
Q
M
T
P
Q
H
M
E
E
L
Dog
Lupus familis
XP_854750
411
45117
S142
S
I
D
L
D
G
G
S
Y
G
K
E
E
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
S130
F
P
F
A
D
T
E
S
F
E
K
E
G
F
H
Rat
Rattus norvegicus
Q5FVM5
470
50844
A166
T
L
Y
P
E
E
Q
A
G
S
P
S
R
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
A170
D
V
S
I
D
L
G
A
W
G
I
P
E
G
S
Chicken
Gallus gallus
XP_424990
441
48727
V133
S
D
M
A
E
G
D
V
S
I
D
L
E
T
W
Frog
Xenopus laevis
A2VD01
525
57606
K130
T
T
P
T
T
K
I
K
V
E
I
P
L
E
E
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
G152
P
Q
A
Q
Q
T
T
G
F
P
L
T
V
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
S172
F
T
H
T
I
S
S
S
P
T
G
S
S
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
0
0
26.6
N.A.
60
6.6
N.A.
0
20
0
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
13.3
13.3
33.3
N.A.
73.3
26.6
N.A.
13.3
26.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
28
0
10
0
19
0
0
0
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% C
% Asp:
10
10
10
0
28
0
19
0
0
10
10
0
0
0
10
% D
% Glu:
0
0
19
0
28
10
19
0
0
19
0
28
37
19
10
% E
% Phe:
28
0
19
0
0
0
0
0
19
0
0
0
0
19
0
% F
% Gly:
0
0
0
10
0
19
19
10
10
19
10
0
19
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
10
0
10
10
0
10
0
0
10
19
0
0
0
0
% I
% Lys:
0
10
0
10
0
10
0
10
0
0
28
0
0
19
0
% K
% Leu:
0
10
0
10
0
10
0
0
0
0
19
10
10
0
10
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% N
% Pro:
10
19
10
10
10
0
0
10
19
10
10
19
10
0
0
% P
% Gln:
0
10
0
10
10
10
10
0
0
10
0
0
0
0
19
% Q
% Arg:
10
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% R
% Ser:
19
0
10
0
0
19
10
37
10
10
0
28
10
0
10
% S
% Thr:
19
19
0
19
19
19
10
10
0
10
0
10
0
19
0
% T
% Val:
0
10
0
0
0
0
0
10
19
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _