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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
8.48
Human Site:
S295
Identified Species:
18.67
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
S295
R
Q
L
R
A
L
P
S
E
D
P
Y
Q
L
E
Chimpanzee
Pan troglodytes
XP_524059
461
49123
L363
V
R
V
F
S
R
T
L
H
N
D
A
A
S
R
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
S272
R
Q
L
R
A
L
P
S
E
N
P
Y
Q
L
E
Dog
Lupus familis
XP_854750
411
45117
R310
A
E
H
G
V
L
S
R
Q
L
R
A
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
S306
R
K
L
R
A
L
P
S
E
D
D
H
Q
P
K
Rat
Rattus norvegicus
Q5FVM5
470
50844
H360
R
V
F
S
R
T
L
H
N
H
A
A
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
G355
R
F
G
C
W
P
P
G
K
R
G
G
R
D
R
Chicken
Gallus gallus
XP_424990
441
48727
K332
Q
I
R
E
F
P
N
K
V
W
Q
A
A
P
A
Frog
Xenopus laevis
A2VD01
525
57606
E423
P
S
Q
Y
S
A
P
E
S
Y
A
A
S
I
V
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
L330
M
R
V
Q
S
R
S
L
H
N
L
Q
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
I349
S
A
R
T
L
L
H
I
K
E
P
T
E
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
0
93.3
6.6
N.A.
66.6
6.6
N.A.
13.3
0
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
20
N.A.
86.6
6.6
N.A.
26.6
6.6
20
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
28
10
0
0
0
0
19
46
19
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
19
19
0
0
10
0
% D
% Glu:
0
10
0
10
0
0
0
10
28
10
0
0
10
0
19
% E
% Phe:
0
10
10
10
10
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
10
0
0
0
10
0
0
10
10
0
0
0
% G
% His:
0
0
10
0
0
0
10
10
19
10
0
10
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
0
10
19
0
0
0
0
0
10
% K
% Leu:
0
0
28
0
10
46
10
19
0
10
10
0
10
19
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
10
28
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
19
46
0
0
0
28
0
0
28
10
% P
% Gln:
10
19
10
10
0
0
0
0
10
0
10
10
28
0
0
% Q
% Arg:
46
19
19
28
10
19
0
10
0
10
10
0
10
10
28
% R
% Ser:
10
10
0
10
28
0
19
28
10
0
0
0
28
19
10
% S
% Thr:
0
0
0
10
0
10
10
0
0
0
0
10
0
0
0
% T
% Val:
10
10
19
0
10
0
0
0
10
0
0
0
0
0
19
% V
% Trp:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
10
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _