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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
11.82
Human Site:
S384
Identified Species:
26
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
S384
G
G
W
L
P
T
G
S
P
S
V
I
L
Q
D
Chimpanzee
Pan troglodytes
XP_524059
461
49123
R451
G
P
S
T
G
S
G
R
A
G
L
E
A
A
G
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
S361
G
G
W
L
P
T
G
S
P
S
V
I
L
Q
D
Dog
Lupus familis
XP_854750
411
45117
S399
G
G
W
L
P
T
H
S
P
T
S
V
I
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
S394
W
Q
P
N
H
S
P
S
L
V
I
F
Q
G
R
Rat
Rattus norvegicus
Q5FVM5
470
50844
E448
G
L
E
I
P
G
E
E
I
W
L
S
W
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
A484
W
A
A
V
A
T
A
A
P
S
I
V
L
Q
T
Chicken
Gallus gallus
XP_424990
441
48727
T428
N
Q
E
W
V
E
R
T
T
S
V
V
I
Q
Q
Frog
Xenopus laevis
A2VD01
525
57606
K513
F
G
H
N
D
T
T
K
V
I
E
L
D
R
T
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
G418
V
T
L
N
P
R
R
G
S
R
R
S
P
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
Y438
T
E
N
Q
A
D
Q
Y
T
T
T
V
V
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
13.3
100
53.3
N.A.
6.6
13.3
N.A.
33.3
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
73.3
N.A.
20
26.6
N.A.
60
40
26.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
19
0
10
10
10
0
0
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
0
0
0
0
10
0
19
% D
% Glu:
0
10
19
0
0
10
10
10
0
0
10
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
46
37
0
0
10
10
28
10
0
10
0
0
0
10
10
% G
% His:
0
0
10
0
10
0
10
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
10
19
19
19
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
28
0
0
0
0
10
0
19
10
28
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
28
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
46
0
10
0
37
0
0
0
10
0
10
% P
% Gln:
0
19
0
10
0
0
10
0
0
0
0
0
10
46
19
% Q
% Arg:
0
0
0
0
0
10
19
10
0
10
10
0
0
10
19
% R
% Ser:
0
0
10
0
0
19
0
37
10
37
10
19
0
0
0
% S
% Thr:
10
10
0
10
0
46
10
10
19
19
10
0
0
0
19
% T
% Val:
10
0
0
10
10
0
0
0
10
10
28
37
10
10
0
% V
% Trp:
19
0
28
10
0
0
0
0
0
10
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _