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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
5.45
Human Site:
S82
Identified Species:
12
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
S82
V
H
H
D
H
T
Y
S
L
P
R
E
T
V
S
Chimpanzee
Pan troglodytes
XP_524059
461
49123
S131
L
S
Y
H
P
G
N
S
C
P
T
T
P
P
G
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
L68
P
A
S
S
L
N
V
L
S
N
S
N
P
C
L
Dog
Lupus familis
XP_854750
411
45117
L104
E
D
F
L
S
S
M
L
S
P
P
A
S
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
L92
L
H
D
H
N
Y
S
L
P
Q
E
H
V
S
I
Rat
Rattus norvegicus
Q5FVM5
470
50844
S128
Q
G
E
G
P
C
P
S
Y
L
P
S
T
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
S132
V
Q
S
E
H
N
Y
S
L
N
V
G
L
L
A
Chicken
Gallus gallus
XP_424990
441
48727
D95
P
F
H
S
S
G
S
D
V
A
S
S
P
Q
S
Frog
Xenopus laevis
A2VD01
525
57606
Q92
L
C
G
D
S
R
P
Q
S
P
F
T
H
A
S
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
S114
V
V
S
Q
T
Q
H
S
L
N
I
N
F
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
V134
M
D
M
S
T
F
L
V
G
S
D
A
M
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
13.3
0
6.6
N.A.
6.6
13.3
N.A.
33.3
13.3
20
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
0
33.3
N.A.
20
13.3
N.A.
53.3
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
10
0
19
0
19
10
% A
% Cys:
0
10
0
0
0
10
0
0
10
0
0
0
0
10
10
% C
% Asp:
0
19
10
19
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
10
0
10
10
0
0
0
0
0
0
10
10
0
0
0
% E
% Phe:
0
10
10
0
0
10
0
0
0
0
10
0
10
0
10
% F
% Gly:
0
10
10
10
0
19
0
0
10
0
0
10
0
0
10
% G
% His:
0
19
19
19
19
0
10
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
28
0
0
10
10
0
10
28
28
10
0
0
10
28
10
% L
% Met:
10
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
10
19
10
0
0
28
0
19
0
0
10
% N
% Pro:
19
0
0
0
19
0
19
0
10
37
19
0
28
19
0
% P
% Gln:
10
10
0
10
0
10
0
10
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
28
28
28
10
19
46
28
10
19
19
10
10
28
% S
% Thr:
0
0
0
0
19
10
0
0
0
0
10
19
19
0
10
% T
% Val:
28
10
0
0
0
0
10
10
10
0
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
19
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _