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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
4.55
Human Site:
S89
Identified Species:
10
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
S89
S
L
P
R
E
T
V
S
M
D
L
G
E
C
E
Chimpanzee
Pan troglodytes
XP_524059
461
49123
G138
S
C
P
T
T
P
P
G
P
V
I
Q
V
P
E
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
L75
L
S
N
S
N
P
C
L
V
H
H
D
H
T
Y
Dog
Lupus familis
XP_854750
411
45117
N111
L
S
P
P
A
S
L
N
V
L
S
S
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
I99
L
P
Q
E
H
V
S
I
D
L
G
E
C
E
M
Rat
Rattus norvegicus
Q5FVM5
470
50844
C135
S
Y
L
P
S
T
A
C
P
E
P
P
R
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
A139
S
L
N
V
G
L
L
A
L
E
E
G
S
P
A
Chicken
Gallus gallus
XP_424990
441
48727
S102
D
V
A
S
S
P
Q
S
S
D
I
V
Q
F
D
Frog
Xenopus laevis
A2VD01
525
57606
S99
Q
S
P
F
T
H
A
S
S
D
D
N
F
S
D
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
F121
S
L
N
I
N
F
P
F
D
F
N
G
W
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
T141
V
G
S
D
A
M
L
T
I
D
A
G
S
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
20
0
6.6
N.A.
0
13.3
N.A.
20
13.3
20
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
6.6
33.3
N.A.
0
26.6
N.A.
46.6
40
26.6
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
19
0
19
10
0
0
10
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
10
10
0
0
0
0
10
10
0
% C
% Asp:
10
0
0
10
0
0
0
0
19
37
10
10
0
10
19
% D
% Glu:
0
0
0
10
10
0
0
0
0
19
10
10
10
19
19
% E
% Phe:
0
0
0
10
0
10
0
10
0
10
0
0
10
10
0
% F
% Gly:
0
10
0
0
10
0
0
10
0
0
10
37
0
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
10
10
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
10
0
19
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
28
28
10
0
0
10
28
10
10
19
10
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
28
0
19
0
0
10
0
0
10
10
0
0
0
% N
% Pro:
0
10
37
19
0
28
19
0
19
0
10
10
0
19
0
% P
% Gln:
10
0
10
0
0
0
10
0
0
0
0
10
10
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
46
28
10
19
19
10
10
28
19
0
10
10
28
10
10
% S
% Thr:
0
0
0
10
19
19
0
10
0
0
0
0
0
28
19
% T
% Val:
10
10
0
10
0
10
10
0
19
10
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _