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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
6.06
Human Site:
T129
Identified Species:
13.33
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
T129
R
K
E
G
T
Q
M
T
P
Q
H
M
E
E
L
Chimpanzee
Pan troglodytes
XP_524059
461
49123
L178
D
L
S
P
R
C
N
L
T
V
K
D
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
E115
Q
H
M
E
E
L
A
E
Q
D
I
V
R
L
V
Dog
Lupus familis
XP_854750
411
45117
T151
G
K
E
E
A
Q
T
T
P
L
Q
V
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
T139
E
K
E
G
F
H
V
T
P
L
P
G
E
E
R
Rat
Rattus norvegicus
Q5FVM5
470
50844
T175
S
P
S
R
F
N
L
T
V
K
E
L
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
D179
G
I
P
E
G
S
G
D
D
G
L
N
P
G
L
Chicken
Gallus gallus
XP_424990
441
48727
C142
I
D
L
E
T
W
M
C
L
E
G
T
N
E
T
Frog
Xenopus laevis
A2VD01
525
57606
P139
E
I
P
L
E
E
T
P
G
L
T
P
S
V
T
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
L161
P
L
T
V
K
D
L
L
L
S
G
T
P
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
L181
T
G
S
S
K
N
I
L
P
M
T
Q
K
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
6.6
0
46.6
N.A.
46.6
6.6
N.A.
6.6
20
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
20
53.3
N.A.
53.3
26.6
N.A.
6.6
26.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
10
0
10
10
10
0
10
0
10
0
% D
% Glu:
19
0
28
37
19
10
0
10
0
10
10
0
28
46
0
% E
% Phe:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
0
19
10
0
10
0
10
10
19
10
0
10
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
19
0
0
0
0
10
0
0
0
10
0
0
0
0
% I
% Lys:
0
28
0
0
19
0
0
0
0
10
10
0
10
0
0
% K
% Leu:
0
19
10
10
0
10
19
28
19
28
10
10
19
28
28
% L
% Met:
0
0
10
0
0
0
19
0
0
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
19
10
0
0
0
0
10
10
0
0
% N
% Pro:
10
10
19
10
0
0
0
10
37
0
10
10
19
0
19
% P
% Gln:
10
0
0
0
0
19
0
0
10
10
10
10
0
0
0
% Q
% Arg:
10
0
0
10
10
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
10
0
28
10
0
10
0
0
0
10
0
0
10
0
10
% S
% Thr:
10
0
10
0
19
0
19
37
10
0
19
19
0
0
19
% T
% Val:
0
0
0
10
0
0
10
0
10
10
0
19
0
10
19
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _