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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
19.7
Human Site:
T248
Identified Species:
43.33
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
T248
V
I
E
I
S
N
K
T
S
S
S
S
T
C
I
Chimpanzee
Pan troglodytes
XP_524059
461
49123
K316
I
V
V
Q
S
T
S
K
S
A
Q
T
G
T
C
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
T225
V
I
E
I
S
N
K
T
S
S
S
S
T
C
I
Dog
Lupus familis
XP_854750
411
45117
L263
L
R
R
L
Q
A
M
L
I
Q
I
S
N
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
T259
V
I
E
I
A
N
K
T
S
S
G
S
T
C
V
Rat
Rattus norvegicus
Q5FVM5
470
50844
P313
V
V
Q
S
T
S
K
P
A
H
A
G
T
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
T308
V
T
Q
T
S
T
K
T
S
S
T
S
T
C
V
Chicken
Gallus gallus
XP_424990
441
48727
T285
V
R
Q
S
T
T
K
T
T
T
A
S
T
C
I
Frog
Xenopus laevis
A2VD01
525
57606
A376
K
V
T
R
S
C
K
A
A
G
T
Q
T
G
T
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
K283
L
V
M
N
G
S
N
K
P
V
Q
A
G
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
T302
V
T
K
T
T
S
K
T
A
Q
A
S
T
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
13.3
100
6.6
N.A.
80
33.3
N.A.
60
46.6
20
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
40
100
20
N.A.
93.3
73.3
N.A.
80
80
40
26.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
10
28
10
28
10
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
64
19
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
10
10
19
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
28
0
28
0
0
0
0
10
0
10
0
0
0
46
% I
% Lys:
10
0
10
0
0
0
73
19
0
0
0
0
0
10
0
% K
% Leu:
19
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
28
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
28
10
10
0
0
0
0
19
19
10
0
0
0
% Q
% Arg:
0
19
10
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
19
46
28
10
0
46
37
19
64
0
0
0
% S
% Thr:
0
19
10
19
28
28
0
55
10
10
19
10
73
19
19
% T
% Val:
64
37
10
0
0
0
0
0
0
10
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _