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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3
All Species:
31.82
Human Site:
Y198
Identified Species:
70
UniProt:
O43889
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43889
NP_006359.3
395
43917
Y198
S
R
R
K
K
K
V
Y
V
G
G
L
E
S
R
Chimpanzee
Pan troglodytes
XP_524059
461
49123
Y267
S
R
K
K
K
K
E
Y
I
D
G
L
E
T
R
Rhesus Macaque
Macaca mulatta
XP_001085696
372
41757
L179
K
K
V
Y
V
G
G
L
E
S
R
V
L
K
Y
Dog
Lupus familis
XP_854750
411
45117
K218
Q
E
S
R
R
K
K
K
V
Y
L
G
G
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61817
404
45093
Y209
S
R
K
K
K
K
V
Y
V
V
G
L
E
S
R
Rat
Rattus norvegicus
Q5FVM5
470
50844
Y263
S
R
K
K
K
K
E
Y
I
D
G
L
E
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515078
497
52525
Y258
S
R
R
K
K
R
V
Y
V
G
G
L
E
S
R
Chicken
Gallus gallus
XP_424990
441
48727
Y235
S
R
R
R
K
K
I
Y
V
D
G
L
E
N
R
Frog
Xenopus laevis
A2VD01
525
57606
Y323
S
R
R
K
K
K
E
Y
M
D
S
L
E
K
R
Zebra Danio
Brachydanio rerio
Q1LYG4
428
48314
Y234
S
R
K
K
K
K
E
Y
I
D
G
L
E
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790412
454
50364
Y252
S
R
K
K
K
K
E
Y
V
D
G
L
E
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.8
89.3
57.9
N.A.
66.3
29.5
N.A.
37
36.2
24
29.2
N.A.
N.A.
N.A.
N.A.
28.8
Protein Similarity:
100
44
91.1
67.8
N.A.
75
45.7
N.A.
49.9
51
39.2
46.7
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
66.6
0
13.3
N.A.
86.6
66.6
N.A.
93.3
73.3
66.6
73.3
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
86.6
13.3
26.6
N.A.
93.3
86.6
N.A.
100
93.3
73.3
86.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
46
0
10
0
0
0
82
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
19
73
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
28
0
0
0
0
0
0
% I
% Lys:
10
10
46
73
82
82
10
10
0
0
0
0
0
19
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
10
82
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
82
37
19
10
10
0
0
0
0
10
0
0
0
82
% R
% Ser:
82
0
10
0
0
0
0
0
0
10
10
0
0
37
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
10
0
10
0
28
0
55
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
82
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _