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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREB3 All Species: 31.82
Human Site: Y198 Identified Species: 70
UniProt: O43889 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43889 NP_006359.3 395 43917 Y198 S R R K K K V Y V G G L E S R
Chimpanzee Pan troglodytes XP_524059 461 49123 Y267 S R K K K K E Y I D G L E T R
Rhesus Macaque Macaca mulatta XP_001085696 372 41757 L179 K K V Y V G G L E S R V L K Y
Dog Lupus familis XP_854750 411 45117 K218 Q E S R R K K K V Y L G G L E
Cat Felis silvestris
Mouse Mus musculus Q61817 404 45093 Y209 S R K K K K V Y V V G L E S R
Rat Rattus norvegicus Q5FVM5 470 50844 Y263 S R K K K K E Y I D G L E N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515078 497 52525 Y258 S R R K K R V Y V G G L E S R
Chicken Gallus gallus XP_424990 441 48727 Y235 S R R R K K I Y V D G L E N R
Frog Xenopus laevis A2VD01 525 57606 Y323 S R R K K K E Y M D S L E K R
Zebra Danio Brachydanio rerio Q1LYG4 428 48314 Y234 S R K K K K E Y I D G L E S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790412 454 50364 Y252 S R K K K K E Y V D G L E H R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.8 89.3 57.9 N.A. 66.3 29.5 N.A. 37 36.2 24 29.2 N.A. N.A. N.A. N.A. 28.8
Protein Similarity: 100 44 91.1 67.8 N.A. 75 45.7 N.A. 49.9 51 39.2 46.7 N.A. N.A. N.A. N.A. 44.7
P-Site Identity: 100 66.6 0 13.3 N.A. 86.6 66.6 N.A. 93.3 73.3 66.6 73.3 N.A. N.A. N.A. N.A. 73.3
P-Site Similarity: 100 86.6 13.3 26.6 N.A. 93.3 86.6 N.A. 100 93.3 73.3 86.6 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 46 0 10 0 0 0 82 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 0 0 19 73 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 10 0 28 0 0 0 0 0 0 % I
% Lys: 10 10 46 73 82 82 10 10 0 0 0 0 0 19 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 10 82 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 82 37 19 10 10 0 0 0 0 10 0 0 0 82 % R
% Ser: 82 0 10 0 0 0 0 0 0 10 10 0 0 37 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 10 0 10 0 28 0 55 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 82 0 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _