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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1C All Species: 39.39
Human Site: S274 Identified Species: 61.9
UniProt: O43896 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43896 NP_006603.2 1103 122947 S274 E G A N I N K S L T T L G K V
Chimpanzee Pan troglodytes XP_511296 1097 122335 S274 E G A N I N K S L T T L G K V
Rhesus Macaque Macaca mulatta XP_001117788 1214 134234 S385 E G A N I N K S L T T L G K V
Dog Lupus familis XP_546571 1191 131317 S361 E G A N I N K S L T T L G K V
Cat Felis silvestris
Mouse Mus musculus O35071 1100 122416 S274 E G A N I N K S L T T L G K V
Rat Rattus norvegicus O35787 1097 122315 S273 E G A N I N K S L T T L G K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 S274 E G A N I N K S L T T L G K V
Chicken Gallus gallus XP_417608 1757 197902 S274 E G A N I N K S L T T L G K V
Frog Xenopus laevis Q91784 1226 138905 T324 A D S N M E E T L N T L R Y A
Zebra Danio Brachydanio rerio XP_699380 1180 133432 L275 G A N I N K S L T T L G K V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 T277 N I N K S L T T L G K V I S A
Honey Bee Apis mellifera XP_397276 1682 191012 L275 G A N I N K S L T T L G K V I
Nematode Worm Caenorhab. elegans P23678 1584 179603 S271 E G A N I N K S L T T L G L V
Sea Urchin Strong. purpuratus P46872 699 78679 Q27 L N S K E T G Q G F K S V V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 K256 G Q T L E E A K K I N K S L S
Conservation
Percent
Protein Identity: 100 99 89.6 87.7 N.A. 94.1 92.7 N.A. 38.1 38.7 23.9 60.4 N.A. 30.7 36.2 30.3 27.6
Protein Similarity: 100 99 89.9 89.3 N.A. 95.5 94.6 N.A. 48.6 48.4 42.3 71.8 N.A. 42.8 47.6 43.5 41
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 26.6 6.6 N.A. 6.6 6.6 93.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 53.3 13.3 N.A. 20 13.3 93.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 60 0 0 0 7 0 0 0 0 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 60 0 0 0 14 14 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 20 60 0 0 0 0 7 0 7 7 0 14 60 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 14 60 0 0 0 0 7 0 0 7 0 14 % I
% Lys: 0 0 0 14 0 14 60 7 7 0 14 7 14 54 7 % K
% Leu: 7 0 0 7 0 7 0 14 74 0 14 67 0 14 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 20 67 14 60 0 0 0 7 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 14 0 7 0 14 60 0 0 0 7 7 7 7 % S
% Thr: 0 0 7 0 0 7 7 14 14 74 67 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 7 7 20 60 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _