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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1C All Species: 24.55
Human Site: S412 Identified Species: 38.57
UniProt: O43896 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43896 NP_006603.2 1103 122947 S412 S S P P A P V S P S S P T T H
Chimpanzee Pan troglodytes XP_511296 1097 122335 S406 S S P P A P V S P S S P T T H
Rhesus Macaque Macaca mulatta XP_001117788 1214 134234 S523 S S P P A P V S P S S P T T H
Dog Lupus familis XP_546571 1191 131317 S499 S S P P A P V S P S H P P A H
Cat Felis silvestris
Mouse Mus musculus O35071 1100 122416 S412 S S P P A P A S P S S P P P H
Rat Rattus norvegicus O35787 1097 122315 S411 S S P P A P A S P S S P P P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 S399 S L T A S P S S C S L S S Q V
Chicken Gallus gallus XP_417608 1757 197902 S399 S L T A S P S S C S L S S Q V
Frog Xenopus laevis Q91784 1226 138905 S482 V Q L Q D E S S G I A G S I E
Zebra Danio Brachydanio rerio XP_699380 1180 133432 L411 G E P H Q P S L P Y V Q S T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 K395 Q E E D E L T K S T V I K S P
Honey Bee Apis mellifera XP_397276 1682 191012 V392 V Q E G D E I V R V V K R E D
Nematode Worm Caenorhab. elegans P23678 1584 179603 Q387 G I D V T D V Q E T P G K H K
Sea Urchin Strong. purpuratus P46872 699 78679 V142 Q E N V R F L V R V S Y L E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Q371 V N L E S E V Q V W R G G E T
Conservation
Percent
Protein Identity: 100 99 89.6 87.7 N.A. 94.1 92.7 N.A. 38.1 38.7 23.9 60.4 N.A. 30.7 36.2 30.3 27.6
Protein Similarity: 100 99 89.9 89.3 N.A. 95.5 94.6 N.A. 48.6 48.4 42.3 71.8 N.A. 42.8 47.6 43.5 41
P-Site Identity: 100 100 100 80 N.A. 80 80 N.A. 26.6 26.6 6.6 26.6 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 100 80 N.A. 80 80 N.A. 40 40 20 33.3 N.A. 13.3 6.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 40 0 14 0 0 0 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 14 7 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 20 14 7 7 20 0 0 7 0 0 0 0 20 7 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 7 0 0 0 0 7 0 0 20 7 0 0 % G
% His: 0 0 0 7 0 0 0 0 0 0 7 0 0 7 40 % H
% Ile: 0 7 0 0 0 0 7 0 0 7 0 7 0 7 7 % I
% Lys: 0 0 0 0 0 0 0 7 0 0 0 7 14 0 7 % K
% Leu: 0 14 14 0 0 7 7 7 0 0 14 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 47 40 0 60 0 0 47 0 7 40 20 14 7 % P
% Gln: 14 14 0 7 7 0 0 14 0 0 0 7 0 14 0 % Q
% Arg: 0 0 0 0 7 0 0 0 14 0 7 0 7 0 0 % R
% Ser: 54 40 0 0 20 0 27 60 7 54 40 14 27 7 7 % S
% Thr: 0 0 14 0 7 0 7 0 0 14 0 0 20 27 7 % T
% Val: 20 0 0 14 0 0 40 14 7 14 20 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _