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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF1C
All Species:
43.94
Human Site:
Y341
Identified Species:
69.05
UniProt:
O43896
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43896
NP_006603.2
1103
122947
Y341
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Chimpanzee
Pan troglodytes
XP_511296
1097
122335
Y341
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Rhesus Macaque
Macaca mulatta
XP_001117788
1214
134234
Y452
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Dog
Lupus familis
XP_546571
1191
131317
Y428
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
O35071
1100
122416
Y341
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Rat
Rattus norvegicus
O35787
1097
122315
Y340
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509769
1770
199343
Y341
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Chicken
Gallus gallus
XP_417608
1757
197902
Y341
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Frog
Xenopus laevis
Q91784
1226
138905
E391
E
N
L
Q
S
L
M
E
R
N
K
N
L
E
K
Zebra Danio
Brachydanio rerio
XP_699380
1180
133432
Y342
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAJ2
1670
189326
Y344
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Honey Bee
Apis mellifera
XP_397276
1682
191012
Y342
E
T
L
S
T
L
R
Y
A
D
R
A
K
Q
I
Nematode Worm
Caenorhab. elegans
P23678
1584
179603
L338
F
D
E
T
L
S
T
L
R
Y
A
D
R
A
K
Sea Urchin
Strong. purpuratus
P46872
699
78679
F94
E
G
Y
N
G
T
I
F
A
Y
G
Q
T
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
F323
E
T
L
S
T
L
R
F
G
M
R
A
K
S
I
Conservation
Percent
Protein Identity:
100
99
89.6
87.7
N.A.
94.1
92.7
N.A.
38.1
38.7
23.9
60.4
N.A.
30.7
36.2
30.3
27.6
Protein Similarity:
100
99
89.9
89.3
N.A.
95.5
94.6
N.A.
48.6
48.4
42.3
71.8
N.A.
42.8
47.6
43.5
41
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
20
93.3
N.A.
93.3
93.3
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
46.6
93.3
N.A.
93.3
93.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
80
0
7
40
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
74
0
7
0
0
0
% D
% Glu:
94
0
7
0
0
0
0
7
0
0
0
0
0
7
0
% E
% Phe:
7
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
0
7
0
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
80
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
7
0
80
0
14
% K
% Leu:
0
0
87
0
7
87
0
7
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
7
0
74
0
% Q
% Arg:
0
0
0
0
0
0
80
0
14
0
80
0
7
0
0
% R
% Ser:
0
0
0
80
7
7
0
0
0
0
0
0
0
7
0
% S
% Thr:
0
80
0
7
80
7
7
0
0
0
0
40
7
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
74
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _