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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL1
All Species:
40.3
Human Site:
S683
Identified Species:
68.21
UniProt:
O43897
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43897
NP_036596.3
1013
114709
S683
V
E
I
W
S
G
L
S
S
E
S
K
L
H
G
Chimpanzee
Pan troglodytes
XP_001150703
1013
114731
S683
V
E
I
W
S
G
L
S
S
E
S
K
L
H
G
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
S683
V
E
I
W
S
G
L
S
S
D
S
K
L
H
G
Dog
Lupus familis
XP_539791
1045
118180
S715
V
E
I
W
S
G
L
S
S
E
S
K
L
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62381
1013
114514
S683
V
E
I
W
S
G
P
S
S
E
S
K
L
H
G
Rat
Rattus norvegicus
NP_001099551
1013
114567
S683
V
E
I
W
S
G
L
S
S
E
S
K
L
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
S684
V
E
V
R
S
G
L
S
S
D
S
K
L
H
G
Chicken
Gallus gallus
Q9DER7
1008
114873
S678
V
E
I
R
S
G
L
S
S
D
S
K
L
H
G
Frog
Xenopus laevis
Q8JI28
1007
114347
S678
V
E
V
R
S
G
L
S
S
D
S
K
L
H
G
Zebra Danio
Brachydanio rerio
O57460
1022
115518
S692
V
E
V
R
S
G
L
S
S
D
S
K
L
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
R705
L
I
I
Y
S
K
M
R
D
N
R
L
K
K
I
Honey Bee
Apis mellifera
XP_393866
1225
138704
G882
V
E
V
S
S
K
L
G
D
D
I
L
R
K
H
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
R638
S
S
D
S
S
V
E
R
D
G
F
F
A
N
F
Sea Urchin
Strong. purpuratus
P98069
639
71875
Y327
S
P
E
W
P
G
Q
Y
D
G
D
Q
T
C
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
89.9
N.A.
93.5
93.5
N.A.
89.2
88.1
85.2
81.1
N.A.
41.5
45
42.5
38.3
Protein Similarity:
100
100
99.6
92.6
N.A.
96.4
96.3
N.A.
94.2
93.9
92.9
90.9
N.A.
59
60
59.2
48.5
P-Site Identity:
100
100
93.3
100
N.A.
93.3
100
N.A.
80
86.6
80
80
N.A.
13.3
26.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
93.3
93.3
93.3
N.A.
33.3
40
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
29
43
8
0
0
0
0
% D
% Glu:
0
79
8
0
0
0
8
0
0
36
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% F
% Gly:
0
0
0
0
0
79
0
8
0
15
0
0
0
0
72
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
8
% H
% Ile:
0
8
58
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
15
0
0
0
0
0
72
8
15
0
% K
% Leu:
8
0
0
0
0
0
72
0
0
0
0
15
72
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
29
0
0
0
15
0
0
8
0
8
0
0
% R
% Ser:
15
8
0
15
93
0
0
72
72
0
72
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
79
0
29
0
0
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _