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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL1
All Species:
43.33
Human Site:
T631
Identified Species:
73.33
UniProt:
O43897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43897
NP_036596.3
1013
114709
T631
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Chimpanzee
Pan troglodytes
XP_001150703
1013
114731
T631
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
T631
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Dog
Lupus familis
XP_539791
1045
118180
T663
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q62381
1013
114514
T631
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Rat
Rattus norvegicus
NP_001099551
1013
114567
T631
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
T632
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Chicken
Gallus gallus
Q9DER7
1008
114873
T626
K
L
N
G
T
I
P
T
P
G
W
P
K
E
Y
Frog
Xenopus laevis
Q8JI28
1007
114347
T626
K
L
N
G
T
I
T
T
P
A
W
P
K
E
Y
Zebra Danio
Brachydanio rerio
O57460
1022
115518
T640
K
L
N
G
T
I
T
T
P
G
W
P
K
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
L647
A
T
K
S
N
G
S
L
Y
S
P
S
Y
P
D
Honey Bee
Apis mellifera
XP_393866
1225
138704
S826
D
S
N
G
T
I
T
S
P
S
F
P
V
T
Y
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
F587
I
F
L
N
F
T
K
F
N
V
E
G
M
K
T
Sea Urchin
Strong. purpuratus
P98069
639
71875
P276
T
I
L
P
R
K
D
P
E
S
G
I
R
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
89.9
N.A.
93.5
93.5
N.A.
89.2
88.1
85.2
81.1
N.A.
41.5
45
42.5
38.3
Protein Similarity:
100
100
99.6
92.6
N.A.
96.4
96.3
N.A.
94.2
93.9
92.9
90.9
N.A.
59
60
59.2
48.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
0
53.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
6.6
66.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
8
0
0
72
8
% E
% Phe:
0
8
0
0
8
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
79
0
8
0
0
0
65
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
79
0
0
0
0
0
8
0
0
0
% I
% Lys:
72
0
8
0
0
8
8
0
0
0
0
0
72
8
0
% K
% Leu:
0
72
15
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
79
8
8
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
8
79
0
8
79
0
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
8
0
0
8
8
0
22
0
8
0
0
0
% S
% Thr:
8
8
0
0
79
8
72
72
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
72
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
79
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _