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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL1
All Species:
46.36
Human Site:
Y291
Identified Species:
78.46
UniProt:
O43897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43897
NP_036596.3
1013
114709
Y291
V
N
S
L
G
E
R
Y
D
F
D
S
I
M
H
Chimpanzee
Pan troglodytes
XP_001150703
1013
114731
Y291
V
N
S
L
G
E
R
Y
D
F
D
S
I
M
H
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
Y291
V
N
S
L
G
E
R
Y
D
F
D
S
I
M
H
Dog
Lupus familis
XP_539791
1045
118180
Y323
V
N
S
L
G
E
R
Y
D
F
D
S
I
M
H
Cat
Felis silvestris
Mouse
Mus musculus
Q62381
1013
114514
Y291
V
N
S
L
G
E
R
Y
D
F
D
S
I
M
H
Rat
Rattus norvegicus
NP_001099551
1013
114567
Y291
V
N
S
L
G
E
R
Y
D
F
D
S
I
M
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
Y292
V
N
S
L
G
E
P
Y
D
F
D
S
I
M
H
Chicken
Gallus gallus
Q9DER7
1008
114873
Y287
V
N
S
L
G
E
P
Y
D
F
D
S
I
M
H
Frog
Xenopus laevis
Q8JI28
1007
114347
Y286
V
H
S
L
G
E
S
Y
D
F
D
S
I
M
H
Zebra Danio
Brachydanio rerio
O57460
1022
115518
Y300
V
N
S
L
G
E
P
Y
D
F
D
S
I
M
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
Y282
V
D
L
P
L
L
P
Y
D
L
N
S
I
M
H
Honey Bee
Apis mellifera
XP_393866
1225
138704
Y482
V
N
S
L
G
L
P
Y
D
Y
D
S
I
M
H
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
H264
S
G
N
L
A
I
Q
H
A
G
V
C
T
W
H
Sea Urchin
Strong. purpuratus
P98069
639
71875
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
89.9
N.A.
93.5
93.5
N.A.
89.2
88.1
85.2
81.1
N.A.
41.5
45
42.5
38.3
Protein Similarity:
100
100
99.6
92.6
N.A.
96.4
96.3
N.A.
94.2
93.9
92.9
90.9
N.A.
59
60
59.2
48.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
93.3
N.A.
46.6
80
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
60
86.6
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
86
0
79
0
0
0
0
% D
% Glu:
0
0
0
0
0
72
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% F
% Gly:
0
8
0
0
79
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
93
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
86
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
86
8
15
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% M
% Asn:
0
72
8
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
36
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
43
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
79
0
0
0
8
0
0
0
0
86
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
86
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _