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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL1
All Species:
46.06
Human Site:
Y675
Identified Species:
77.95
UniProt:
O43897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43897
NP_036596.3
1013
114709
Y675
N
E
V
C
K
Y
D
Y
V
E
I
W
S
G
L
Chimpanzee
Pan troglodytes
XP_001150703
1013
114731
Y675
N
E
V
C
K
Y
D
Y
V
E
I
W
S
G
L
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
Y675
N
E
V
C
K
Y
D
Y
V
E
I
W
S
G
L
Dog
Lupus familis
XP_539791
1045
118180
Y707
N
E
V
C
K
Y
D
Y
V
E
I
W
S
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q62381
1013
114514
Y675
N
E
V
C
K
Y
D
Y
V
E
I
W
S
G
P
Rat
Rattus norvegicus
NP_001099551
1013
114567
Y675
N
E
V
C
K
Y
D
Y
V
E
I
W
S
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
Y676
N
E
V
C
K
Y
D
Y
V
E
V
R
S
G
L
Chicken
Gallus gallus
Q9DER7
1008
114873
Y670
N
E
V
C
K
Y
D
Y
V
E
I
R
S
G
L
Frog
Xenopus laevis
Q8JI28
1007
114347
Y670
N
E
V
C
K
Y
D
Y
V
E
V
R
S
G
L
Zebra Danio
Brachydanio rerio
O57460
1022
115518
Y684
N
E
V
C
K
Y
D
Y
V
E
V
R
S
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
Y697
Y
T
K
C
N
Y
D
Y
L
I
I
Y
S
K
M
Honey Bee
Apis mellifera
XP_393866
1225
138704
S874
Q
Q
E
C
E
Y
D
S
V
E
V
S
S
K
L
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
F630
R
N
R
V
R
I
E
F
S
S
D
S
S
V
E
Sea Urchin
Strong. purpuratus
P98069
639
71875
S319
L
E
S
T
G
N
F
S
S
P
E
W
P
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
89.9
N.A.
93.5
93.5
N.A.
89.2
88.1
85.2
81.1
N.A.
41.5
45
42.5
38.3
Protein Similarity:
100
100
99.6
92.6
N.A.
96.4
96.3
N.A.
94.2
93.9
92.9
90.9
N.A.
59
60
59.2
48.5
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
93.3
86.6
86.6
N.A.
40
46.6
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
93.3
93.3
93.3
N.A.
60
66.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
86
0
0
0
8
0
0
0
0
% D
% Glu:
0
79
8
0
8
0
8
0
0
79
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
79
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
58
0
0
0
0
% I
% Lys:
0
0
8
0
72
0
0
0
0
0
0
0
0
15
0
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
72
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
0
8
0
8
0
0
0
0
0
0
29
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
15
15
8
0
15
93
0
0
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
72
8
0
0
0
0
79
0
29
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% W
% Tyr:
8
0
0
0
0
86
0
79
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _