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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
11.21
Human Site:
S381
Identified Species:
22.42
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S381
A
P
G
P
S
R
R
S
W
S
A
G
P
V
T
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
A417
G
S
D
S
S
D
S
A
F
Q
N
A
R
A
K
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S381
A
P
G
P
G
R
R
S
W
S
A
G
T
V
T
Dog
Lupus familis
XP_851538
620
68996
W385
S
G
T
G
R
Q
S
W
S
A
G
T
V
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
S381
A
P
G
P
G
R
R
S
W
S
A
G
T
V
T
Rat
Rattus norvegicus
Q71QF9
831
94152
K528
L
E
C
L
S
D
L
K
P
E
Q
S
V
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
A365
G
S
D
S
S
D
S
A
F
Q
N
A
R
A
K
Chicken
Gallus gallus
XP_001234704
864
97886
A353
G
S
D
S
S
D
S
A
F
Q
S
A
R
A
K
Frog
Xenopus laevis
Q90WV2
832
94675
T582
E
K
M
S
N
M
G
T
L
N
S
S
M
L
N
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
S383
S
C
D
S
A
L
Q
S
K
S
A
T
H
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
P439
P
S
D
T
S
S
G
P
Q
L
R
P
T
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
L487
D
T
G
R
E
T
S
L
K
R
S
K
D
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
6.6
86.6
0
N.A.
86.6
6.6
N.A.
6.6
6.6
0
20
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
20
86.6
20
N.A.
86.6
6.6
N.A.
20
26.6
33.3
40
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
9
0
0
25
0
9
34
25
0
25
9
% A
% Cys:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
42
0
0
34
0
0
0
0
0
0
9
0
9
% D
% Glu:
9
9
0
0
9
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% F
% Gly:
25
9
34
9
17
0
17
0
0
0
9
25
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
9
17
0
0
9
0
9
25
% K
% Leu:
9
0
0
9
0
9
9
9
9
9
0
0
0
9
0
% L
% Met:
0
0
9
0
0
9
0
0
0
0
0
0
9
9
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
17
0
0
0
9
% N
% Pro:
9
25
0
25
0
0
0
9
9
0
0
9
9
0
9
% P
% Gln:
0
0
0
0
0
9
9
0
9
25
9
0
0
0
0
% Q
% Arg:
0
0
0
9
9
25
25
0
0
9
9
0
25
9
9
% R
% Ser:
17
34
0
42
50
9
42
34
9
34
25
17
0
9
9
% S
% Thr:
0
9
9
9
0
9
0
9
0
0
0
17
25
0
25
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
17
25
0
% V
% Trp:
0
0
0
0
0
0
0
9
25
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _