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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
9.39
Human Site:
S445
Identified Species:
18.79
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S445
M
P
E
L
G
L
R
S
V
P
E
P
P
P
E
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
N481
S
S
Q
T
P
S
L
N
R
D
P
I
W
R
S
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S445
M
P
E
L
G
L
R
S
A
P
E
P
P
P
E
Dog
Lupus familis
XP_851538
620
68996
G449
M
P
E
L
G
L
R
G
P
P
E
P
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
S445
M
P
E
L
G
L
R
S
A
P
E
P
P
T
E
Rat
Rattus norvegicus
Q71QF9
831
94152
A592
S
S
M
L
H
R
S
A
E
S
L
K
S
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
N429
S
S
Q
T
P
S
L
N
R
D
H
I
W
R
S
Chicken
Gallus gallus
XP_001234704
864
97886
H417
T
P
S
L
N
R
E
H
V
W
R
S
R
D
E
Frog
Xenopus laevis
Q90WV2
832
94675
E646
N
G
D
Y
G
S
I
E
I
R
Q
P
P
M
S
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
T447
D
P
P
P
Y
G
R
T
S
T
P
H
P
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
L503
A
A
G
V
A
D
L
L
L
G
G
G
V
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
H551
R
P
Q
P
P
P
R
H
P
S
H
T
Q
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
0
93.3
80
N.A.
86.6
6.6
N.A.
0
26.6
20
20
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
93.3
80
N.A.
86.6
13.3
N.A.
13.3
26.6
40
26.6
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
0
9
17
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
0
0
0
17
0
0
0
9
9
% D
% Glu:
0
0
34
0
0
0
9
9
9
0
34
0
0
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
42
9
0
9
0
9
9
9
0
0
17
% G
% His:
0
0
0
0
9
0
0
17
0
0
17
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
0
0
17
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
50
0
34
25
9
9
0
9
0
0
17
0
% L
% Met:
34
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
9
0
0
17
0
0
0
0
0
0
9
% N
% Pro:
0
59
9
17
25
9
0
0
17
34
17
42
50
34
9
% P
% Gln:
0
0
25
0
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
9
0
0
0
0
17
50
0
17
9
9
0
9
17
0
% R
% Ser:
25
25
9
0
0
25
9
25
9
17
0
9
9
0
25
% S
% Thr:
9
0
0
17
0
0
0
9
0
9
0
9
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
17
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _