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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
8.48
Human Site:
S453
Identified Species:
16.97
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S453
V
P
E
P
P
P
E
S
P
G
Q
P
N
L
R
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
R489
R
D
P
I
W
R
S
R
E
E
P
Y
H
Y
G
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S453
A
P
E
P
P
P
E
S
P
G
Q
P
N
L
R
Dog
Lupus familis
XP_851538
620
68996
L457
P
P
E
P
P
P
G
L
P
S
Q
P
D
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
S453
A
P
E
P
P
T
E
S
P
G
H
P
A
P
H
Rat
Rattus norvegicus
Q71QF9
831
94152
S600
E
S
L
K
S
L
N
S
E
L
C
P
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
R437
R
D
H
I
W
R
S
R
D
E
L
Y
H
Y
G
Chicken
Gallus gallus
XP_001234704
864
97886
L425
V
W
R
S
R
D
E
L
Y
H
Y
G
S
K
M
Frog
Xenopus laevis
Q90WV2
832
94675
E654
I
R
Q
P
P
M
S
E
R
S
R
R
R
V
Y
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
S455
S
T
P
H
P
L
P
S
A
Q
L
C
P
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
M511
L
G
G
G
V
P
G
M
P
R
P
A
H
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
A559
P
S
H
T
Q
V
D
A
R
M
H
G
G
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
0
93.3
53.3
N.A.
60
13.3
N.A.
0
13.3
13.3
13.3
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
6.6
93.3
60
N.A.
60
13.3
N.A.
6.6
20
40
20
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
9
9
0
0
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% C
% Asp:
0
17
0
0
0
9
9
0
9
0
0
0
9
0
0
% D
% Glu:
9
0
34
0
0
0
34
9
17
17
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
9
0
0
17
0
0
25
0
17
9
0
17
% G
% His:
0
0
17
9
0
0
0
0
0
9
17
0
25
0
9
% H
% Ile:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
0
% K
% Leu:
9
0
9
0
0
17
0
17
0
9
17
0
0
17
0
% L
% Met:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
17
0
0
% N
% Pro:
17
34
17
42
50
34
9
0
42
0
17
42
9
25
17
% P
% Gln:
0
0
9
0
9
0
0
0
0
9
25
0
0
0
0
% Q
% Arg:
17
9
9
0
9
17
0
17
17
9
9
9
9
0
17
% R
% Ser:
9
17
0
9
9
0
25
42
0
17
0
0
9
0
0
% S
% Thr:
0
9
0
9
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
9
9
0
0
0
0
0
0
0
17
9
% V
% Trp:
0
9
0
0
17
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
9
17
0
17
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _