KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
5.15
Human Site:
S464
Identified Species:
10.3
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S464
P
N
L
R
P
D
D
S
A
F
G
R
Q
S
T
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
E500
Y
H
Y
G
N
K
M
E
Q
N
Q
T
Q
S
P
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S464
P
N
L
R
P
D
D
S
A
F
G
R
Q
S
T
Dog
Lupus familis
XP_851538
620
68996
G468
P
D
P
P
L
E
D
G
A
F
G
R
Q
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
N464
P
A
P
H
P
D
D
N
A
F
G
R
Q
S
T
Rat
Rattus norvegicus
Q71QF9
831
94152
E611
P
E
K
I
I
P
E
E
K
P
V
H
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
E448
Y
H
Y
G
N
K
M
E
Q
S
Q
S
Q
S
P
Chicken
Gallus gallus
XP_001234704
864
97886
Q436
G
S
K
M
E
Q
G
Q
A
Q
S
P
L
Q
L
Frog
Xenopus laevis
Q90WV2
832
94675
E665
R
R
V
Y
N
F
E
E
R
S
Q
R
P
H
H
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
A466
C
P
V
A
N
D
R
A
G
S
L
S
K
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
L522
A
H
P
P
P
I
D
L
T
E
L
G
I
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
T570
G
G
A
V
D
F
R
T
A
T
N
T
I
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
13.3
100
60
N.A.
73.3
6.6
N.A.
13.3
6.6
6.6
6.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
73.3
N.A.
80
13.3
N.A.
20
13.3
20
26.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
9
0
0
0
9
50
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
34
42
0
0
0
0
0
0
9
0
% D
% Glu:
0
9
0
0
9
9
17
34
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
17
0
0
0
34
0
0
0
0
0
% F
% Gly:
17
9
0
17
0
0
9
9
9
0
34
9
0
9
9
% G
% His:
0
25
0
9
0
0
0
0
0
0
0
9
0
9
9
% H
% Ile:
0
0
0
9
9
9
0
0
0
0
0
0
17
0
0
% I
% Lys:
0
0
17
0
0
17
0
0
9
0
0
0
9
0
0
% K
% Leu:
0
0
17
0
9
0
0
9
0
0
17
0
17
0
17
% L
% Met:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
34
0
0
9
0
9
9
0
0
0
0
% N
% Pro:
42
9
25
17
34
9
0
0
0
9
0
9
9
9
17
% P
% Gln:
0
0
0
0
0
9
0
9
17
9
25
0
50
9
9
% Q
% Arg:
9
9
0
17
0
0
17
0
9
0
0
42
0
0
0
% R
% Ser:
0
9
0
0
0
0
0
17
0
25
9
17
0
59
0
% S
% Thr:
0
0
0
0
0
0
0
9
9
9
0
17
0
0
34
% T
% Val:
0
0
17
9
0
0
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
17
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _