KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
18.79
Human Site:
S538
Identified Species:
37.58
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S538
H
Y
Q
C
D
A
G
S
G
S
D
S
E
S
C
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
S580
E
S
Y
S
D
M
S
S
Q
S
F
S
E
T
R
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S540
H
Y
Q
C
D
A
G
S
G
S
D
S
G
S
C
Dog
Lupus familis
XP_851538
620
68996
S543
H
H
Q
C
D
L
G
S
G
S
D
S
G
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
S547
H
H
R
C
D
L
G
S
G
S
D
S
G
S
C
Rat
Rattus norvegicus
Q71QF9
831
94152
G753
P
G
M
T
R
F
L
G
L
Y
G
D
D
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
S549
Y
D
E
E
E
G
E
S
G
M
P
T
Q
Q
C
Chicken
Gallus gallus
XP_001234704
864
97886
G533
K
Y
E
E
E
E
E
G
G
M
P
T
P
Q
C
Frog
Xenopus laevis
Q90WV2
832
94675
L754
V
A
G
K
F
L
G
L
Y
G
E
D
E
D
S
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
Y705
R
N
T
S
L
T
L
Y
S
S
R
S
R
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
S669
R
R
R
N
Q
S
R
S
S
S
E
M
Q
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
M757
T
R
T
V
S
S
H
M
K
Y
D
K
Y
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
33.3
93.3
80
N.A.
73.3
0
N.A.
20
20
13.3
13.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
40
93.3
86.6
N.A.
86.6
6.6
N.A.
53.3
40
20
13.3
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
17
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
50
% C
% Asp:
0
9
0
0
42
0
0
0
0
0
42
17
9
17
9
% D
% Glu:
9
0
17
17
17
9
17
0
0
0
17
0
25
0
9
% E
% Phe:
0
0
0
0
9
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
9
0
0
9
42
17
50
9
9
0
25
0
0
% G
% His:
34
17
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
9
25
17
9
9
0
0
0
0
0
0
% L
% Met:
0
0
9
0
0
9
0
9
0
17
0
9
0
0
0
% M
% Asn:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
17
0
9
0
0
% P
% Gln:
0
0
25
0
9
0
0
0
9
0
0
0
17
17
0
% Q
% Arg:
17
17
17
0
9
0
9
0
0
0
9
0
9
0
17
% R
% Ser:
0
9
0
17
9
17
9
59
17
59
0
50
0
34
9
% S
% Thr:
9
0
17
9
0
9
0
0
0
0
0
17
0
9
0
% T
% Val:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
25
9
0
0
0
0
9
9
17
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _