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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
14.24
Human Site:
S548
Identified Species:
28.48
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S548
D
S
E
S
C
S
S
S
P
S
S
S
S
S
E
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
I590
F
S
E
T
R
G
S
I
Q
V
P
K
Y
E
E
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S550
D
S
G
S
C
S
S
S
P
S
S
S
S
S
E
Dog
Lupus familis
XP_851538
620
68996
S553
D
S
G
S
C
S
S
S
P
S
S
P
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
S557
D
S
G
S
C
S
S
S
P
S
S
P
S
S
E
Rat
Rattus norvegicus
Q71QF9
831
94152
C763
G
D
D
D
D
S
W
C
S
S
S
T
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
R559
P
T
Q
Q
C
R
T
R
H
P
I
N
A
L
K
Chicken
Gallus gallus
XP_001234704
864
97886
R543
P
T
P
Q
C
R
T
R
H
P
I
N
A
L
K
Frog
Xenopus laevis
Q90WV2
832
94675
S764
E
D
E
D
S
W
C
S
T
C
S
S
S
S
S
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
C715
R
S
R
H
E
D
S
C
S
T
C
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
N679
E
M
Q
I
N
Q
T
N
L
R
L
H
N
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
D767
D
K
Y
N
R
Y
E
D
D
D
Y
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
26.6
93.3
86.6
N.A.
86.6
33.3
N.A.
6.6
6.6
40
33.3
N.A.
0
N.A.
N.A.
26.6
P-Site Similarity:
100
33.3
93.3
86.6
N.A.
86.6
46.6
N.A.
46.6
40
46.6
40
N.A.
46.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
17
9
0
% A
% Cys:
0
0
0
0
50
0
9
17
0
9
9
0
0
0
0
% C
% Asp:
42
17
9
17
9
9
0
9
9
9
0
0
0
0
0
% D
% Glu:
17
0
25
0
9
0
9
0
0
0
0
0
0
9
42
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
25
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
17
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
17
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
17
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
9
0
0
17
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
9
0
0
0
17
9
0
0
% N
% Pro:
17
0
9
0
0
0
0
0
34
17
9
17
0
0
0
% P
% Gln:
0
0
17
17
0
9
0
0
9
0
0
0
0
0
9
% Q
% Arg:
9
0
9
0
17
17
0
17
0
9
0
0
0
0
0
% R
% Ser:
0
50
0
34
9
42
50
42
17
42
50
42
67
67
34
% S
% Thr:
0
17
0
9
0
0
25
0
9
9
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _