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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
12.73
Human Site:
S590
Identified Species:
25.45
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
S590
T
A
M
E
T
F
N
S
P
S
L
S
L
P
R
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
A694
S
S
M
Q
F
R
S
A
E
S
V
R
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
S592
N
A
T
E
T
F
N
S
P
S
L
S
L
P
R
Dog
Lupus familis
XP_851538
620
68996
S595
N
A
T
G
T
P
K
S
P
S
P
Q
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
S599
T
S
T
E
T
F
N
S
P
A
Q
P
L
V
Q
Rat
Rattus norvegicus
Q71QF9
831
94152
T795
P
Q
R
F
T
Y
Y
T
D
D
L
S
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
A640
S
S
M
Q
F
R
S
A
E
S
V
R
S
L
L
Chicken
Gallus gallus
XP_001234704
864
97886
A624
S
S
V
Q
F
R
S
A
E
S
V
R
S
L
L
Frog
Xenopus laevis
Q90WV2
832
94675
S796
P
Q
R
Y
Q
Y
F
S
D
D
L
C
S
P
T
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
G749
T
G
Q
R
A
D
E
G
Q
T
E
D
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
V741
G
G
V
R
V
A
Y
V
P
N
D
A
L
A
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
L811
A
R
V
Q
I
N
T
L
P
T
V
H
Y
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
13.3
86.6
53.3
N.A.
53.3
26.6
N.A.
13.3
6.6
20
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
53.3
86.6
53.3
N.A.
73.3
40
N.A.
53.3
53.3
26.6
20
N.A.
33.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
0
0
9
9
0
25
0
9
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
17
17
9
9
0
0
0
% D
% Glu:
0
0
0
25
0
0
9
0
25
0
9
0
9
9
0
% E
% Phe:
0
0
0
9
25
25
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
0
9
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
17
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
34
0
42
25
25
% L
% Met:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
9
25
0
0
9
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
9
0
0
50
0
9
9
0
50
0
% P
% Gln:
0
17
9
34
9
0
0
0
9
0
9
9
0
0
9
% Q
% Arg:
0
9
17
17
0
25
0
0
0
0
0
25
0
0
25
% R
% Ser:
25
34
0
0
0
0
25
42
0
50
0
25
42
0
0
% S
% Thr:
25
0
25
0
42
0
9
9
0
17
0
0
0
0
9
% T
% Val:
0
0
25
0
9
0
0
9
0
0
34
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
17
17
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _