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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
12.73
Human Site:
T414
Identified Species:
25.45
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
T414
T
T
T
K
G
T
S
T
E
L
A
P
A
T
G
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
L450
M
L
N
Q
H
S
Q
L
Q
V
S
S
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
T414
T
T
T
K
G
T
C
T
E
S
A
P
A
T
G
Dog
Lupus familis
XP_851538
620
68996
T418
T
A
T
K
G
T
S
T
E
P
G
P
V
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
T414
T
A
S
K
G
T
C
T
K
A
E
P
A
A
G
Rat
Rattus norvegicus
Q71QF9
831
94152
Y561
S
K
P
R
P
S
L
Y
S
L
Q
N
F
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
L398
M
L
N
P
C
G
Q
L
Q
V
T
S
N
R
L
Chicken
Gallus gallus
XP_001234704
864
97886
T386
A
L
S
Q
L
Q
V
T
S
N
R
L
S
T
D
Frog
Xenopus laevis
Q90WV2
832
94675
H615
P
P
E
E
K
P
M
H
T
S
A
L
R
R
S
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
A416
I
S
I
Q
R
T
P
A
A
N
G
G
Q
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
H472
R
D
P
G
R
K
A
H
H
G
H
P
K
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
R520
R
S
A
M
Q
D
R
R
R
K
A
N
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
0
86.6
66.6
N.A.
53.3
6.6
N.A.
0
13.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
86.6
66.6
N.A.
66.6
26.6
N.A.
13.3
33.3
13.3
20
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
0
0
0
9
9
9
9
34
0
25
17
0
% A
% Cys:
0
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
9
0
0
0
0
25
0
9
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
34
9
0
0
0
9
17
9
0
0
34
% G
% His:
0
0
0
0
9
0
0
17
9
0
9
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
9
0
34
9
9
0
0
9
9
0
0
9
0
0
% K
% Leu:
0
25
0
0
9
0
9
17
0
17
0
17
0
0
17
% L
% Met:
17
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
17
0
17
17
0
0
% N
% Pro:
9
9
17
9
9
9
9
0
0
9
0
42
0
0
0
% P
% Gln:
0
0
0
25
9
9
17
0
17
0
9
0
9
0
0
% Q
% Arg:
17
0
0
9
17
0
9
9
9
0
9
0
9
25
0
% R
% Ser:
9
17
17
0
0
17
17
0
17
17
9
17
17
9
17
% S
% Thr:
34
17
25
0
0
42
0
42
9
0
9
0
0
25
17
% T
% Val:
0
0
0
0
0
0
9
0
0
17
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _