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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRICKLE3 All Species: 15.76
Human Site: T489 Identified Species: 31.52
UniProt: O43900 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43900 NP_006141.2 615 68609 T489 S E G G P R R T L S A P P A Q
Chimpanzee Pan troglodytes XP_001174634 936 105835 Q525 T S Y S P G G Q G A G A Q P E
Rhesus Macaque Macaca mulatta XP_001105952 620 69149 T489 S E G G P R R T L S A P P A Q
Dog Lupus familis XP_851538 620 68996 T493 S E G G P R R T L S A P P A Q
Cat Felis silvestris
Mouse Mus musculus Q80VL3 624 69709 T489 S E G G P R R T L S A P P A Q
Rat Rattus norvegicus Q71QF9 831 94152 D636 Q Q V K F S D D V I D N G S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508261 882 99961 V473 T S Y S P G Q V A G A Q P D L
Chicken Gallus gallus XP_001234704 864 97886 S461 N P S Q V P G S Q P D L W A K
Frog Xenopus laevis Q90WV2 832 94675 A690 S E N A L H L A T D S K P S G
Zebra Danio Brachydanio rerio XP_698649 783 87844 E491 S A L E F T V E L N G Y A E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U1I1 785 86590 T547 F G D T Q T L T N S M P D M L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194491 836 95332 Q595 T P Q H K R Y Q T P Y T A Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.8 96.4 88 N.A. 88.1 36.9 N.A. 40.4 41.3 36.2 50.7 N.A. 36.3 N.A. N.A. 37.2
Protein Similarity: 100 50.6 97.2 90.6 N.A. 89.9 48.6 N.A. 51.4 51.5 47.9 59.9 N.A. 48.4 N.A. N.A. 49.7
P-Site Identity: 100 6.6 100 100 N.A. 100 0 N.A. 20 6.6 20 13.3 N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 20 N.A. 33.3 26.6 33.3 20 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 9 9 9 42 9 17 42 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 9 9 0 9 17 0 9 9 0 % D
% Glu: 0 42 0 9 0 0 0 9 0 0 0 0 0 9 9 % E
% Phe: 9 0 0 0 17 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 9 34 34 0 17 17 0 9 9 17 0 9 0 9 % G
% His: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 9 9 0 0 0 0 0 0 9 0 0 9 % K
% Leu: 0 0 9 0 9 0 17 0 42 0 0 9 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % M
% Asn: 9 0 9 0 0 0 0 0 9 9 0 9 0 0 0 % N
% Pro: 0 17 0 0 50 9 0 0 0 17 0 42 50 9 0 % P
% Gln: 9 9 9 9 9 0 9 17 9 0 0 9 9 9 42 % Q
% Arg: 0 0 0 0 0 42 34 0 0 0 0 0 0 0 0 % R
% Ser: 50 17 9 17 0 9 0 9 0 42 9 0 0 17 0 % S
% Thr: 25 0 0 9 0 17 0 42 17 0 0 9 0 0 0 % T
% Val: 0 0 9 0 9 0 9 9 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 17 0 0 0 9 0 0 0 9 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _