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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRICKLE3
All Species:
35.76
Human Site:
Y290
Identified Species:
71.52
UniProt:
O43900
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43900
NP_006141.2
615
68609
Y290
A
S
L
G
G
Q
R
Y
V
M
R
Q
S
R
P
Chimpanzee
Pan troglodytes
XP_001174634
936
105835
Y326
T
V
L
G
G
Q
R
Y
I
M
K
E
G
R
P
Rhesus Macaque
Macaca mulatta
XP_001105952
620
69149
Y290
A
S
L
G
G
Q
R
Y
V
M
R
Q
S
R
P
Dog
Lupus familis
XP_851538
620
68996
Y290
A
S
L
G
G
Q
R
Y
V
M
R
Q
S
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL3
624
69709
Y290
A
S
L
G
G
Q
R
Y
V
M
R
Q
S
R
P
Rat
Rattus norvegicus
Q71QF9
831
94152
F293
A
S
L
L
G
C
P
F
L
P
K
Q
G
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508261
882
99961
Y274
T
V
L
G
G
Q
R
Y
I
M
K
E
G
R
P
Chicken
Gallus gallus
XP_001234704
864
97886
Y262
T
V
L
G
G
Q
R
Y
I
M
K
D
G
R
P
Frog
Xenopus laevis
Q90WV2
832
94675
D450
E
N
I
K
G
K
N
D
L
Q
R
N
N
R
N
Zebra Danio
Brachydanio rerio
XP_698649
783
87844
Y289
A
A
L
G
G
Q
R
Y
I
M
R
E
S
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1I1
785
86590
Y348
H
Q
L
G
G
Q
R
Y
I
M
R
E
G
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194491
836
95332
Y356
T
Q
L
G
G
Q
R
Y
I
M
R
E
G
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.8
96.4
88
N.A.
88.1
36.9
N.A.
40.4
41.3
36.2
50.7
N.A.
36.3
N.A.
N.A.
37.2
Protein Similarity:
100
50.6
97.2
90.6
N.A.
89.9
48.6
N.A.
51.4
51.5
47.9
59.9
N.A.
48.4
N.A.
N.A.
49.7
P-Site Identity:
100
60
100
100
N.A.
100
33.3
N.A.
60
60
20
80
N.A.
60
N.A.
N.A.
60
P-Site Similarity:
100
80
100
100
N.A.
100
60
N.A.
80
73.3
53.3
100
N.A.
80
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
84
100
0
0
0
0
0
0
0
50
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
50
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
34
0
0
9
0
% K
% Leu:
0
0
92
9
0
0
0
0
17
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
0
0
0
9
9
0
9
% N
% Pro:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
84
% P
% Gln:
0
17
0
0
0
84
0
0
0
9
0
42
0
9
0
% Q
% Arg:
0
0
0
0
0
0
84
0
0
0
67
0
0
75
0
% R
% Ser:
0
42
0
0
0
0
0
0
0
0
0
0
42
0
0
% S
% Thr:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
25
0
0
0
0
0
0
34
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _