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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAS2
All Species:
35.76
Human Site:
S227
Identified Species:
87.41
UniProt:
O43903
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43903
NP_001137302.1
313
34945
S227
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Chimpanzee
Pan troglodytes
XP_509301
694
75137
S238
R
F
S
I
E
Y
L
S
E
G
R
Y
R
L
G
Rhesus Macaque
Macaca mulatta
XP_001091603
313
34947
S227
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Dog
Lupus familis
XP_534091
313
34872
S227
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Cat
Felis silvestris
Mouse
Mus musculus
P11862
314
34882
S228
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Rat
Rattus norvegicus
NP_001120976
314
34912
S228
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509170
314
35197
S228
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Chicken
Gallus gallus
XP_420902
314
35258
S228
K
F
C
V
E
R
L
S
Q
G
R
Y
R
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685440
265
29446
T191
E
P
P
L
S
P
V
T
P
A
S
Y
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780477
305
34184
S225
V
T
D
I
H
R
I
S
E
G
K
Y
N
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.5
98.4
98
N.A.
97.1
96.8
N.A.
90.7
91.7
N.A.
49.8
N.A.
N.A.
N.A.
N.A.
40.2
Protein Similarity:
100
35.7
99.3
99
N.A.
98
97.7
N.A.
95.8
95.5
N.A.
64.8
N.A.
N.A.
N.A.
N.A.
57.8
P-Site Identity:
100
60
100
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
80
0
0
0
20
0
0
0
0
0
0
% E
% Phe:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
90
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
70
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
80
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
10
0
0
10
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
70
0
0
0
0
10
0
% Q
% Arg:
10
0
0
0
0
80
0
0
0
0
80
0
80
0
0
% R
% Ser:
0
0
10
0
10
0
0
90
0
0
10
0
10
0
10
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
10
0
0
70
0
0
10
0
0
0
0
0
0
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
100
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _