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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAS2 All Species: 27.88
Human Site: Y299 Identified Species: 68.15
UniProt: O43903 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43903 NP_001137302.1 313 34945 Y299 K D M N P D N Y L V V S A S Y
Chimpanzee Pan troglodytes XP_509301 694 75137 R310 S V P D S P A R T P Q P P E M
Rhesus Macaque Macaca mulatta XP_001091603 313 34947 Y299 K D M N P D N Y L V V S A N Y
Dog Lupus familis XP_534091 313 34872 Y299 K D M N P D N Y L V V S A N Y
Cat Felis silvestris
Mouse Mus musculus P11862 314 34882 Y300 K D M N P D N Y L V V S A T Y
Rat Rattus norvegicus NP_001120976 314 34912 Y300 K D M N P D N Y L V V S A T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509170 314 35197 Y300 K D L S P D N Y L V V S A H Y
Chicken Gallus gallus XP_420902 314 35258 Y300 R D M N P D N Y L V V S A H Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685440 265 29446 Q252 F C I E R Q S Q G R Y R V G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780477 305 34184 S292 L P L V F V S S V P C V L S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.5 98.4 98 N.A. 97.1 96.8 N.A. 90.7 91.7 N.A. 49.8 N.A. N.A. N.A. N.A. 40.2
Protein Similarity: 100 35.7 99.3 99 N.A. 98 97.7 N.A. 95.8 95.5 N.A. 64.8 N.A. N.A. N.A. N.A. 57.8
P-Site Identity: 100 0 93.3 93.3 N.A. 93.3 93.3 N.A. 80 86.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 0 70 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 70 0 10 0 70 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % E
% Phe: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 20 0 0 0 0 0 70 0 0 0 10 0 0 % L
% Met: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 60 0 0 70 0 0 0 0 0 0 20 0 % N
% Pro: 0 10 10 0 70 10 0 0 0 20 0 10 10 0 0 % P
% Gln: 0 0 0 0 0 10 0 10 0 0 10 0 0 0 0 % Q
% Arg: 10 0 0 0 10 0 0 10 0 10 0 10 0 0 10 % R
% Ser: 10 0 0 10 10 0 20 10 0 0 0 70 0 20 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 20 0 % T
% Val: 0 10 0 10 0 10 0 0 10 70 70 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 10 0 0 0 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _