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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXTL3
All Species:
7.27
Human Site:
T305
Identified Species:
12.31
UniProt:
O43909
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43909
NP_001431.1
919
104749
T305
V
A
Q
S
T
F
Y
T
V
Q
Y
R
P
G
F
Chimpanzee
Pan troglodytes
XP_001166624
919
104712
T305
V
A
Q
S
T
F
Y
T
V
Q
Y
R
P
G
F
Rhesus Macaque
Macaca mulatta
XP_001111377
724
82688
S160
E
K
I
E
S
L
R
S
S
L
Q
E
A
R
S
Dog
Lupus familis
XP_850237
919
104592
A305
V
A
Q
S
T
F
Y
A
S
Q
Y
R
P
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL6
918
104529
A305
A
Q
S
T
L
Y
A
A
Q
Y
R
A
G
F
D
Rat
Rattus norvegicus
NP_064482
919
104425
A305
V
A
Q
S
T
F
Y
A
A
Q
Y
R
A
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505771
333
35563
Chicken
Gallus gallus
XP_420030
919
105127
D305
L
A
Q
S
T
F
Y
D
V
Q
Y
R
P
G
F
Frog
Xenopus laevis
NP_001085848
919
105285
D305
I
A
Q
S
T
F
Y
D
L
Q
Y
R
P
G
F
Zebra Danio
Brachydanio rerio
Q5IGR7
741
85103
A177
K
T
K
V
Q
S
L
A
L
W
N
N
G
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ08
972
110981
S345
L
A
R
R
D
L
T
S
H
R
T
N
P
L
Y
Honey Bee
Apis mellifera
XP_397082
948
108470
R326
I
V
Q
S
T
F
F
R
N
Q
F
R
E
G
F
Nematode Worm
Caenorhab. elegans
O01705
814
94178
H250
N
F
Q
S
K
S
I
H
V
Q
A
S
K
I
R
Sea Urchin
Strong. purpuratus
XP_790713
948
109252
N329
V
V
Q
T
P
F
V
N
S
Q
F
R
S
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
78.5
98.4
N.A.
96.9
97.2
N.A.
29.8
90.8
87.6
27.4
N.A.
48.4
48.6
33.5
50.6
Protein Similarity:
100
99.8
78.5
99
N.A.
97.7
98.2
N.A.
32.4
96.1
95
44.5
N.A.
64.9
66.8
51.6
69.8
P-Site Identity:
100
100
0
86.6
N.A.
0
80
N.A.
0
86.6
80
0
N.A.
13.3
53.3
26.6
46.6
P-Site Similarity:
100
100
13.3
86.6
N.A.
13.3
80
N.A.
0
93.3
93.3
13.3
N.A.
46.6
73.3
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
0
0
0
8
29
8
0
8
8
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
15
0
0
0
0
0
0
8
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
8
0
0
0
58
8
0
0
0
15
0
0
8
58
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
15
58
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
15
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
15
0
0
0
8
15
8
0
15
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
8
0
8
15
0
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
43
0
0
% P
% Gln:
0
8
65
0
8
0
0
0
8
65
8
0
0
0
0
% Q
% Arg:
0
0
8
8
0
0
8
8
0
8
8
58
0
15
8
% R
% Ser:
0
0
8
58
8
15
0
15
22
0
0
8
8
0
8
% S
% Thr:
0
8
0
15
50
0
8
15
0
0
8
0
0
0
0
% T
% Val:
36
15
0
8
0
0
8
0
29
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
43
0
0
8
43
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _