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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC5L All Species: 19.09
Human Site: S84 Identified Species: 38.18
UniProt: O43913 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43913 NP_002544.1 435 50283 S84 L N K L N H L S S S E D G C S
Chimpanzee Pan troglodytes XP_519292 593 67095 S242 L N K L N H L S S S E D G C S
Rhesus Macaque Macaca mulatta XP_001085300 547 62537 S196 L N K L N H L S S S E D G C S
Dog Lupus familis XP_852382 607 68559 C256 L N K L N H L C S S E D G C S
Cat Felis silvestris
Mouse Mus musculus Q9WUV0 435 50199 N84 L N K L S H L N S S D A G C S
Rat Rattus norvegicus NP_001014208 435 50085 S84 L N K L S H L S S S E A E C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508134 435 50005 S84 L N R L D C L S S S E N G C S
Chicken Gallus gallus NP_001025900 447 51705 H96 I L I Q L Q N H S S E T R R A
Frog Xenopus laevis NP_001089444 448 51945 Q97 L N H L H D H Q P A P E N E F
Zebra Danio Brachydanio rerio NP_998363 444 50748 D98 L S A L F G P D S A A L L P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24169 460 52097 S87 M L E I L L D S L A P D Q G D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184572 451 51144 G99 L N Q V A E A G P S P E N G F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.3 78.9 69 N.A. 93.7 92.6 N.A. 88.7 79.8 76.3 65.7 N.A. 35.8 N.A. N.A. 58.5
Protein Similarity: 100 73.3 79.1 70.8 N.A. 97.9 96.7 N.A. 94.9 89.2 86.1 80.1 N.A. 56.9 N.A. N.A. 74.7
P-Site Identity: 100 100 100 93.3 N.A. 73.3 80 N.A. 73.3 20 20 20 N.A. 13.3 N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 93.3 33.3 40 33.3 N.A. 40 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 0 9 0 0 25 9 17 0 0 9 % A
% Cys: 0 0 0 0 0 9 0 9 0 0 0 0 0 59 0 % C
% Asp: 0 0 0 0 9 9 9 9 0 0 9 42 0 0 9 % D
% Glu: 0 0 9 0 0 9 0 0 0 0 59 17 9 9 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 17 % F
% Gly: 0 0 0 0 0 9 0 9 0 0 0 0 50 17 0 % G
% His: 0 0 9 0 9 50 9 9 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 84 17 0 75 17 9 59 0 9 0 0 9 9 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 75 0 0 34 0 9 9 0 0 0 9 17 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 17 0 25 0 0 9 0 % P
% Gln: 0 0 9 9 0 9 0 9 0 0 0 0 9 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 9 9 9 % R
% Ser: 0 9 0 0 17 0 0 50 75 75 0 0 0 0 59 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _