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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC5L All Species: 35.76
Human Site: T250 Identified Species: 71.52
UniProt: O43913 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43913 NP_002544.1 435 50283 T250 G E A S E R D T R K L W R N I
Chimpanzee Pan troglodytes XP_519292 593 67095 T408 G E A S E R D T R K L W R N I
Rhesus Macaque Macaca mulatta XP_001085300 547 62537 T362 G E A S E R D T R K L W R N I
Dog Lupus familis XP_852382 607 68559 T422 G E A N E R D T R K L W R N I
Cat Felis silvestris
Mouse Mus musculus Q9WUV0 435 50199 T250 G E A G E R D T R K L W R N I
Rat Rattus norvegicus NP_001014208 435 50085 T250 G E A G E R D T R K L W R N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508134 435 50005 T250 G E A S E R D T R K L W R N I
Chicken Gallus gallus NP_001025900 447 51705 T262 K E A K E R D T R K L W K N I
Frog Xenopus laevis NP_001089444 448 51945 S263 G E A K E T D S H K L W K N I
Zebra Danio Brachydanio rerio NP_998363 444 50748 I259 G E A K E S D I H K L W K N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24169 460 52097 S256 L T A R K C L S T Y L E P V L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184572 451 51144 A265 G E A T V D D A H K L W R N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.3 78.9 69 N.A. 93.7 92.6 N.A. 88.7 79.8 76.3 65.7 N.A. 35.8 N.A. N.A. 58.5
Protein Similarity: 100 73.3 79.1 70.8 N.A. 97.9 96.7 N.A. 94.9 89.2 86.1 80.1 N.A. 56.9 N.A. N.A. 74.7
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 100 80 66.6 66.6 N.A. 13.3 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 86.6 80 73.3 N.A. 33.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 100 0 0 0 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 92 0 0 0 0 0 0 0 0 % D
% Glu: 0 92 0 0 84 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 84 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 92 % I
% Lys: 9 0 0 25 9 0 0 0 0 92 0 0 25 0 0 % K
% Leu: 9 0 0 0 0 0 9 0 0 0 100 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 0 92 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 67 0 0 67 0 0 0 67 0 0 % R
% Ser: 0 0 0 34 0 9 0 17 0 0 0 0 0 0 0 % S
% Thr: 0 9 0 9 0 9 0 67 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 92 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _