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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYROBP
All Species:
23.64
Human Site:
Y102
Identified Species:
47.27
UniProt:
O43914
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43914
NP_003323.1
113
12179
Y102
Q
G
Q
R
S
D
V
Y
S
D
L
N
T
Q
R
Chimpanzee
Pan troglodytes
A4F4L0
113
12201
Y102
Q
G
Q
R
S
D
V
Y
S
D
L
N
M
Q
R
Rhesus Macaque
Macaca mulatta
Q8WNQ8
113
12113
Y102
Q
G
Q
R
S
D
V
Y
S
D
L
N
T
Q
R
Dog
Lupus familis
XP_533687
175
18859
Y164
Q
G
Q
R
S
D
V
Y
S
D
L
N
T
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
O54885
114
12349
Y103
Q
G
Q
R
P
E
V
Y
S
D
L
N
T
Q
R
Rat
Rattus norvegicus
Q6X9T7
114
12343
Y103
Q
G
Q
R
P
E
V
Y
S
D
L
N
T
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515771
204
21296
P145
R
P
A
A
R
L
P
P
P
Q
C
P
R
P
A
Chicken
Gallus gallus
NP_990843
175
19348
Y165
G
E
R
N
D
G
Q
Y
S
Q
L
A
T
A
K
Frog
Xenopus laevis
NP_001121359
104
11699
D94
E
L
R
D
H
R
M
D
I
Y
N
D
L
S
R
Zebra Danio
Brachydanio rerio
NP_001093573
115
12960
Q103
Y
Q
E
L
Y
G
V
Q
S
D
I
Y
S
D
L
Tiger Blowfish
Takifugu rubipres
NP_001033072
173
19367
N158
N
D
H
Y
Q
P
L
N
H
K
G
Q
K
D
T
Fruit Fly
Dros. melanogaster
NP_001138035
77
8194
G67
E
S
V
Q
S
G
Y
G
K
I
K
D
V
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
98.2
49.7
N.A.
73.6
71
N.A.
31.3
20.5
30
42.6
20.8
29.2
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
99.1
54.8
N.A.
80.6
78.9
N.A.
40.2
36
48.6
59.1
35.8
38
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
86.6
86.6
N.A.
0
26.6
6.6
20
0
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
6.6
40
33.3
40
6.6
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
0
0
0
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
9
9
34
0
9
0
59
0
17
0
17
0
% D
% Glu:
17
9
9
0
0
17
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
50
0
0
0
25
0
9
0
0
9
0
0
0
0
% G
% His:
0
0
9
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
9
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
9
9
0
9
0
9
% K
% Leu:
0
9
0
9
0
9
9
0
0
0
59
0
9
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
0
9
0
0
0
9
0
0
9
50
0
0
0
% N
% Pro:
0
9
0
0
17
9
9
9
9
0
0
9
0
9
0
% P
% Gln:
50
9
50
9
9
0
9
9
0
17
0
9
0
50
0
% Q
% Arg:
9
0
17
50
9
9
0
0
0
0
0
0
9
0
59
% R
% Ser:
0
9
0
0
42
0
0
0
67
0
0
0
9
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
9
% T
% Val:
0
0
9
0
0
0
59
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
9
0
9
59
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _